Co-infection of Mycoplasma pneumonia and Herpes Simplex Virus (HSV): A Case Report of a Boy with Erythema Multiforme

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Abstract

Background: Erythema multiforme (EM) is an immune-mediated self-limited reaction that has mucocutaneous eruption manifestation.

Aim: The aim of this case report is to acknowledging the possibility of coinfection in EM to give the proper treatment.

Case Description: We report a unique case of Mycoplasma pneumonia and Herpes Simplex Virus-2 positive in immunocompetent patient with erythema multiforme. Coinfection of Mycoplasma pneumonia and Herpes Simplex Virus (HSV) infection is rarely presenting in an immunocompetent patient. The patient was admitted with a worsening blister and erosion on oral and genital mucosa, along with rashes on the extremities and trunk. The patient also had a fluctuating fever and productive cough. The skin examination showed multiple erythematous papules and plaques with dusky area and blister in some central plaques that resembled target lesion. The patient tested positive for Mycoplasma pneumonia and Herpes Simplex Virus (HSV) IgM and IgG serology. The patient received supportive therapy, levofloxacin, acyclovir, methylprednisolone, and therapy for ocular, oral, and skin lesions. Systemic symptoms and cutaneous lesion improved after hospitalization without sequelae.


Conclusion: Although it is rare, coinfection must be taken into consideration for the cause of EM.
Original languageEnglish
JournalAsia Pacific Journal of Pediatrics and Child Health
Volume6
Publication statusPublished - 2023

Keywords

  • Erythema multiforme
  • Mycoplasma pneumonia
  • herpes simplex virus
  • mucocutanous eruption
  • Case-report

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