This paper presents networking design strategies in cloud infrastructure built using Openstack platform and explore scalability issues related to its infrastructure. Experiments discussed in this paper are conducted to study the performance of Openstack network based on the implementation of Neutron in order to provide recommendations for optimal network design suitable for high performance computing. Network performance parameters such as throughput, packet loss and latency were evaluated based on TCP and UDP data transmission using IPerf benchmarking tool. The results show that in general, Openstack did not exhibit network bandwidth bottlenecks. However, the location where virtual machine was instantiated and how the network was segmented will affect network performance. This paper also discussed the traffic flow used to analyze the network performances of different virtual machine’s network topology in the cloud and provide an optimal cloud networking design and recommendations that yields to a better high-performance computing platform.