Chronic neutrophilic leukemia: A case report

Rahmat Cahyanur, Tammy Nurhardini, Maria Angela Putri Maharan, Sri Suryo Adiyanti, Wulyo Rajabto, Muhammad Ikhsan, Endang Farihatul Izza

Research output: Contribution to journalArticlepeer-review


Objectives. We present a case report of a patient with malaise, abdominal pain, and vomiting, later underwent bone marrow biopsy and found to have CNL with no genetic mutation. Case presentation. A 40 years old male came into hospital with malaise, abdominal pain, nausea, and vomiting. Furthermore there were bilateral lymphadenopathy in the neck, hepatomegaly and moderate splenomegaly in abdominal examination. Anemia, leukocytosis and increase of Lactat Dehydrogenase (LDH) were found. Bone marrow aspiration and biopsy was performed and showed predominant neutrophil and the bone marrow biopsy showed hypercellular bone marrow with increased myeloid-neutrophil, increased myeloid erythroid ratio. Outcome. After further investigation this patient was diagnosed with chronic neutrophilic leukemia based on bone marrow aspiration and biopsy result.

Original languageEnglish
Pages (from-to)143-145
Number of pages3
JournalRomanian Medical Journal
Issue number3
Publication statusPublished - 2023


  • Abdominal pain
  • Anemia
  • Bone marrow biopsy
  • Hepatomegaly
  • Leukemia
  • Leukocytosis
  • Lymphadenopathy
  • Malaise
  • Nausea
  • Splenomegaly
  • Vomiting


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