Chronic neutrophilic leukemia: A case report

Rahmat Cahyanur; Tammy Nurhardini; Maria Angela Putri Maharan; Sri Suryo Adiyanti; Wulyo Rajabto; Muhammad Ikhsan; Endang Farihatul Izza

doi:10.37897/RMJ.2023.3.6

Chronic neutrophilic leukemia: A case report

Rahmat Cahyanur, Tammy Nurhardini, Maria Angela Putri Maharan, Sri Suryo Adiyanti, Wulyo Rajabto, Muhammad Ikhsan, Endang Farihatul Izza

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives. We present a case report of a patient with malaise, abdominal pain, and vomiting, later underwent bone marrow biopsy and found to have CNL with no genetic mutation. Case presentation. A 40 years old male came into hospital with malaise, abdominal pain, nausea, and vomiting. Furthermore there were bilateral lymphadenopathy in the neck, hepatomegaly and moderate splenomegaly in abdominal examination. Anemia, leukocytosis and increase of Lactat Dehydrogenase (LDH) were found. Bone marrow aspiration and biopsy was performed and showed predominant neutrophil and the bone marrow biopsy showed hypercellular bone marrow with increased myeloid-neutrophil, increased myeloid erythroid ratio. Outcome. After further investigation this patient was diagnosed with chronic neutrophilic leukemia based on bone marrow aspiration and biopsy result.

Original language	English
Pages (from-to)	143-145
Number of pages	3
Journal	Romanian Medical Journal
Volume	70
Issue number	3
DOIs	https://doi.org/10.37897/RMJ.2023.3.6
Publication status	Published - 2023

Keywords

Abdominal pain
Anemia
Bone marrow biopsy
Hepatomegaly
Leukemia
Leukocytosis
Lymphadenopathy
Malaise
Nausea
Splenomegaly
Vomiting

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.37897/RMJ.2023.3.6

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@article{b033dacc778340fe9729a1f81802d4ba,

title = "Chronic neutrophilic leukemia: A case report",

abstract = "Objectives. We present a case report of a patient with malaise, abdominal pain, and vomiting, later underwent bone marrow biopsy and found to have CNL with no genetic mutation. Case presentation. A 40 years old male came into hospital with malaise, abdominal pain, nausea, and vomiting. Furthermore there were bilateral lymphadenopathy in the neck, hepatomegaly and moderate splenomegaly in abdominal examination. Anemia, leukocytosis and increase of Lactat Dehydrogenase (LDH) were found. Bone marrow aspiration and biopsy was performed and showed predominant neutrophil and the bone marrow biopsy showed hypercellular bone marrow with increased myeloid-neutrophil, increased myeloid erythroid ratio. Outcome. After further investigation this patient was diagnosed with chronic neutrophilic leukemia based on bone marrow aspiration and biopsy result.",

keywords = "Abdominal pain, Anemia, Bone marrow biopsy, Hepatomegaly, Leukemia, Leukocytosis, Lymphadenopathy, Malaise, Nausea, Splenomegaly, Vomiting",

author = "Rahmat Cahyanur and Tammy Nurhardini and Maharan, {Maria Angela Putri} and Adiyanti, {Sri Suryo} and Wulyo Rajabto and Muhammad Ikhsan and Izza, {Endang Farihatul}",

year = "2023",

doi = "10.37897/RMJ.2023.3.6",

language = "English",

volume = "70",

pages = "143--145",

journal = "Romanian Medical Journal",

issn = "1220-5478",

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TY - JOUR

T1 - Chronic neutrophilic leukemia

T2 - A case report

AU - Cahyanur, Rahmat

AU - Nurhardini, Tammy

AU - Maharan, Maria Angela Putri

AU - Adiyanti, Sri Suryo

AU - Rajabto, Wulyo

AU - Ikhsan, Muhammad

AU - Izza, Endang Farihatul

PY - 2023

Y1 - 2023

N2 - Objectives. We present a case report of a patient with malaise, abdominal pain, and vomiting, later underwent bone marrow biopsy and found to have CNL with no genetic mutation. Case presentation. A 40 years old male came into hospital with malaise, abdominal pain, nausea, and vomiting. Furthermore there were bilateral lymphadenopathy in the neck, hepatomegaly and moderate splenomegaly in abdominal examination. Anemia, leukocytosis and increase of Lactat Dehydrogenase (LDH) were found. Bone marrow aspiration and biopsy was performed and showed predominant neutrophil and the bone marrow biopsy showed hypercellular bone marrow with increased myeloid-neutrophil, increased myeloid erythroid ratio. Outcome. After further investigation this patient was diagnosed with chronic neutrophilic leukemia based on bone marrow aspiration and biopsy result.

AB - Objectives. We present a case report of a patient with malaise, abdominal pain, and vomiting, later underwent bone marrow biopsy and found to have CNL with no genetic mutation. Case presentation. A 40 years old male came into hospital with malaise, abdominal pain, nausea, and vomiting. Furthermore there were bilateral lymphadenopathy in the neck, hepatomegaly and moderate splenomegaly in abdominal examination. Anemia, leukocytosis and increase of Lactat Dehydrogenase (LDH) were found. Bone marrow aspiration and biopsy was performed and showed predominant neutrophil and the bone marrow biopsy showed hypercellular bone marrow with increased myeloid-neutrophil, increased myeloid erythroid ratio. Outcome. After further investigation this patient was diagnosed with chronic neutrophilic leukemia based on bone marrow aspiration and biopsy result.

KW - Abdominal pain

KW - Anemia

KW - Bone marrow biopsy

KW - Hepatomegaly

KW - Leukemia

KW - Leukocytosis

KW - Lymphadenopathy

KW - Malaise

KW - Nausea

KW - Splenomegaly

KW - Vomiting

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U2 - 10.37897/RMJ.2023.3.6

DO - 10.37897/RMJ.2023.3.6

M3 - Article

AN - SCOPUS:85185942543

SN - 1220-5478

VL - 70

SP - 143

EP - 145

JO - Romanian Medical Journal

JF - Romanian Medical Journal

IS - 3

ER -

Chronic neutrophilic leukemia: A case report

Abstract

Keywords

UN SDGs

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