Cholestasis sepsis at neonatology ward and neonatal intensive care unit Cipto Mangunkusumo hospital 2007: Incidence, mortality rate and associated risk factors

Kadim Sungkono Bachtiar, Hanifah Oswari, Jose R.L Batubara, Idham Amir, Abdul Latief, Kemas Firman

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Cholestatic jaundice represents serious pathological condition. Septic-cholestasis is a kind of hepato-cellular cholestasis that occured during or after sepsis caused by biliary flow obstruction. This is a cohort study from February to June 2007 on neonatal sepsis patients at Neonatology ward Department of Child Health Faculty of Medicine University of Indonesia-Cipto Mangunkusumo General National Hospital. Aim of this study is to find out the incidence of intrahepatic cholestasis in neonatal sepsis, associated risk factors, and mortality rate in neonatal cholestasis-sepsis. From 138 neonatal sepsis patients, the incidence of intrahepatic cholestasis is 65.9%. None of the risk factors tested in this study showed statistically significant result. Mortality rate of neonatal cholestasis-sepsis is 52.8%.

Original languageEnglish
Pages (from-to)107-113
Number of pages7
JournalMedical Journal of Indonesia
Volume17
Issue number2
DOIs
Publication statusPublished - 1 Apr 2008

Keywords

  • Cholestasis intrahepatic
  • Cholestasis sepsis
  • Conjugated hyperbilirubinemia
  • Neonatal sepsis

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