@inproceedings{808fd8f345fa4cfdba972049f020ecfd,
title = "Chitosan microparticles for in vitro release of acetogenins extracted from Annona muricata L. leaves",
abstract = "Chitosan microparticles were prepared for extended release of acetogenins extracted from the leaves of Annona muricata L., known as soursop. The acetogenin extract was encapsulated in chitosan microparticles prepared using sodium tripolyphosphate as the crosslinking agent. The possible interactions between the microparticle components were analyzed based on their FTIR absorption peaks. The effect of the experimental variables (acetogenin to chitosan mass ratio, amount of tripolyphosphate, presence of enzymes) on the 24-h in vitro cumulative release of acetogenins encapsulated in the chitosan microparticles and immersed in simulated gastrointestinal fluids, is presented. The sequential release in simulated (gastric, intestinal, colonic) fluids for 24 h period, facilitated higher cumulative release of acetogenins, indicating the potential of acetogenin-loaded microparticles for anticancer therapy purposes.",
author = "Elsa Krisanti and Farah Fauzia and Kamarza Mulia",
note = "Funding Information: This research was funded by Universitas Indonesia through PUTI Saintekes research scheme contract number NKB-2442/UN2.RST/HKP.05.00/2020. Publisher Copyright: {\textcopyright} 2021 Author(s).; 3rd International Conference on Chemistry, Chemical Process and Engineering, IC3PE 2020 ; Conference date: 30-09-2020",
year = "2021",
month = sep,
day = "1",
doi = "10.1063/5.0062455",
language = "English",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Is Fatimah and Won-Chun Oh and Imam Sahroni",
booktitle = "3rd International Conference on Chemistry, Chemical Process and Engineering, IC3PE 2020",
address = "United States",
}