Aim: To study the bioactive chemical constituents of Garcinia maingayii Hook. Methods: Repeated column chromatography was used for separation of compounds and spectroscopic techniques and X-ray analysis were used for structure determination. Results: Five known compounds, isoxanthochymol (1), camboginol (2) 5, 7, 2′, 5′-tetrahydroxy flavan-3-o1 (3), stigmasterol (4) and griffipavixanthone (5) were obtained from hexane and acetone extracts of stem barks of the plant. Compounds 1, 2 and 5 showed high potential in vitro cytotoxicity against in P388 murine leukemia cells with IC50 1.47, 4.90 and 0.42 μg·mL-1, respectively. Conclusion: Compounds 1-5 were first reported from this plant.
|Number of pages||5|
|Journal||Chinese Journal of Natural Medicines|
|Publication status||Published - Jul 2007|
- Garcinia maingayii