Chemical constituents of Garcinia maingayii

Sri Hartati, Hong Bing Wang, L. B.S. Kardono, Soleh Kosela, Guo Wei Qin

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Aim: To study the bioactive chemical constituents of Garcinia maingayii Hook. Methods: Repeated column chromatography was used for separation of compounds and spectroscopic techniques and X-ray analysis were used for structure determination. Results: Five known compounds, isoxanthochymol (1), camboginol (2) 5, 7, 2′, 5′-tetrahydroxy flavan-3-o1 (3), stigmasterol (4) and griffipavixanthone (5) were obtained from hexane and acetone extracts of stem barks of the plant. Compounds 1, 2 and 5 showed high potential in vitro cytotoxicity against in P388 murine leukemia cells with IC50 1.47, 4.90 and 0.42 μg·mL-1, respectively. Conclusion: Compounds 1-5 were first reported from this plant.

Original languageEnglish
Pages (from-to)272-276
Number of pages5
JournalChinese Journal of Natural Medicines
Volume5
Issue number4
Publication statusPublished - 1 Jan 2007

Keywords

  • Camboginol
  • Cytoxicity
  • Garcinia maingayii
  • Isoxanthochymol

Fingerprint Dive into the research topics of 'Chemical constituents of Garcinia maingayii'. Together they form a unique fingerprint.

Cite this