@inproceedings{d1794468fba44fb3bc34a792e4b10532,
title = "Characterization of polylactic co-glycolic acid nanospheres modified with PVA and DDAB",
abstract = "The common treatment for diabetic retinopathy is corticosteroids intravitreal injection that sometimes lead to complications. Dexamethasone-loaded polylactic co-glycolic acid (PLGA) nanospheres, modified with dioctadecyldimethylammonium bromide (DDAB) as the cationic surfactant, is expected to prolong drug retention time. Zeta potential of the PLGA nanospheres prepared using non-ionic surfactant PVA and DDAB confirmed the cationic surfactant increase the surface charge of the PLGA nanospheres. The optimal formulation based on the particle size and high positive surface charge was the PLGA-DDAB nanospheres. SEM analysis showed spherical morphology of the nanospheres having diameter 626.9 ± 98.01 nm positive zeta potential of +22.5 mV.",
keywords = "cationic surfactant, Controlled drug release, dioctadecyldimethylammonium bromide, PLGA",
author = "Kamarza Mulia and Dwiantari Satyapertiwi and Ranee Devina and Krisanti, {Elsa Anisa}",
year = "2017",
month = feb,
day = "21",
doi = "10.1063/1.4976767",
language = "English",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Yudan Whulanza and Sugeng Supriadi and Muhamad Sahlan and Basari",
booktitle = "Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices",
note = "1st International Symposium of Biomedical Engineering: Biomedical Engineering's Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2016 ; Conference date: 31-05-2016 Through 01-06-2016",
}