Abstract
This paper presents key properties and examples of applications of resonant leaky-mode biosensors operating in the subwavelength regime. The main resonance features observed under variation of input wavelength and angle are discussed. The dependence of the resonance lineshape on element design parameters is highlighted. The surface-localized power concentration at resonance is described along with the standing-wave pattern of the leaky modes obtained at normal incidence. An example fabrication process involving holographic patterning, etching, and deposition of high-index material is provided. The fabricated elements resonate well with good agreement between experiment and theory found. As examples of practical applications, experimental results on detection of proteins and bacteria are given. The tag-free resonant sensor technology demonstrated may be feasible for use in fields such as in medical diagnostics, drug development, environmental monitoring, and homeland security.
| Original language | English |
|---|---|
| Article number | 60080U |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 6008 |
| DOIs | |
| Publication status | Published - 2005 |
| Event | Nanosensing: Materials and Devices II - Boston, MA, United States Duration: 23 Oct 2005 → 26 Oct 2005 |
Keywords
- Bacterial detection
- Biosensors
- Guided-mode resonance effect
- Leaky modes
- Periodic elements
- Protein defection