Characteristics of resonant leaky-mode biosensors

R. Magnusson, Y. Ding, K. J. Lee, Purnomo Sidi Priambodo, D. Wawro

Research output: Contribution to journalConference articlepeer-review

26 Citations (Scopus)


This paper presents key properties and examples of applications of resonant leaky-mode biosensors operating in the subwavelength regime. The main resonance features observed under variation of input wavelength and angle are discussed. The dependence of the resonance lineshape on element design parameters is highlighted. The surface-localized power concentration at resonance is described along with the standing-wave pattern of the leaky modes obtained at normal incidence. An example fabrication process involving holographic patterning, etching, and deposition of high-index material is provided. The fabricated elements resonate well with good agreement between experiment and theory found. As examples of practical applications, experimental results on detection of proteins and bacteria are given. The tag-free resonant sensor technology demonstrated may be feasible for use in fields such as in medical diagnostics, drug development, environmental monitoring, and homeland security.

Original languageEnglish
Article number60080U
JournalProceedings of SPIE - The International Society for Optical Engineering
Publication statusPublished - 2005
EventNanosensing: Materials and Devices II - Boston, MA, United States
Duration: 23 Oct 200526 Oct 2005


  • Bacterial detection
  • Biosensors
  • Guided-mode resonance effect
  • Leaky modes
  • Periodic elements
  • Protein defection


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