TY - JOUR
T1 - CHARACTERISTICS OF PEDIATRIC BRAIN TUMORS AT DEPARTMENT OF CHILD HEALTH FACULTY OF MEDICINE UNIVERSITAS INDONESIA-DR. CIPTO MANGUNKUSUMO TERTIARY GENERAL HOSPITAL, JAKARTA, INDONESIA
AU - RAFLI, ACHMAD
AU - Soebadi, RR. Amanda
AU - Handryastuti, Setyo
AU - Pusponegoro, Hardiono D.
AU - Siregar, Marsintauli
AU - Mangunatmadja, Irawan
AU - Putro, Widodo Dwi
PY - 2020
Y1 - 2020
N2 - Brain tumors are still the second leading cause of death among cancers in children. Based on data from National Brain Tumor Society (2019), in United States, there are 28.000 children living with brain tumor with varied clinical, radiological, and histopathological features. The most prevalent children’s brain tumor types in US are gliomas (ependymal tumors, pilocytic astrocytomas) and embroyonal tumors, including medulloblastoma. From 1993–1994 at Department of Child Health Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo Tertiary General Hospital, Jakarta, Indonesia, there are 19 patients with brain tumors hospitalized with most of patients with astrocytoma 8 patients (42%), 4 patients (21%) medulloblastoma, 2 patients (11%) neuroblastoma, 2 patients (11%) ependymoma, 2 patients (11%) craniopharyngioma, and one patient (4%) meningioma. Retrospective cohort study (2010–2015) with subjects 100 children revealed that based on the radiographs, the brain tumors were located mostly in the cerebellum (24%) and the suprasellar region (10%); based on the histopathology, the most common types of brain tumor were astrocytomas (18%), medulloblastoma (21%), and gliomas (17%). The most common symptom of brain tumors was headache and impaired vision. Survival patients with brain tumors for 5 years in the age group aged 3 years and above was better than that in children aged under 3 years (60% vs 55% and 17% vs 14%). This report can serve as one of basic data for profile children’s brain tumors in Indonesia.
AB - Brain tumors are still the second leading cause of death among cancers in children. Based on data from National Brain Tumor Society (2019), in United States, there are 28.000 children living with brain tumor with varied clinical, radiological, and histopathological features. The most prevalent children’s brain tumor types in US are gliomas (ependymal tumors, pilocytic astrocytomas) and embroyonal tumors, including medulloblastoma. From 1993–1994 at Department of Child Health Faculty of Medicine Universitas Indonesia-Dr. Cipto Mangunkusumo Tertiary General Hospital, Jakarta, Indonesia, there are 19 patients with brain tumors hospitalized with most of patients with astrocytoma 8 patients (42%), 4 patients (21%) medulloblastoma, 2 patients (11%) neuroblastoma, 2 patients (11%) ependymoma, 2 patients (11%) craniopharyngioma, and one patient (4%) meningioma. Retrospective cohort study (2010–2015) with subjects 100 children revealed that based on the radiographs, the brain tumors were located mostly in the cerebellum (24%) and the suprasellar region (10%); based on the histopathology, the most common types of brain tumor were astrocytomas (18%), medulloblastoma (21%), and gliomas (17%). The most common symptom of brain tumors was headache and impaired vision. Survival patients with brain tumors for 5 years in the age group aged 3 years and above was better than that in children aged under 3 years (60% vs 55% and 17% vs 14%). This report can serve as one of basic data for profile children’s brain tumors in Indonesia.
M3 - Article
SN - 1522-8517
JO - Neuro-Oncology
JF - Neuro-Oncology
ER -
