Characteristics and outcome of acute respiratory failure patients: A cross-sectional study from the National Referral Hospital for Respiratory Diseases

Menaldi Rasmin, Mia Elhidsi, Wiendo Syahputra Yahya

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction. Acute respiratory failure (ARF) is the consequence of the aggravation of various diseases. The aim of this study is to provide the clinical characteristics and the evolution of patients with ARF. Method. This was a cross-sectional study. Data were taken from the hospital registry of patients with ARF from January to December 2015. The statistical analysis was performed using Pearson chi-square and its alternative to analyze proportion difference and logistic regression in order to evaluate influencing intrahospital mortality factors. Results. This study involved 150 patients with ARF, of which 86% had respiratory failure in the emergency ward. The median age was 51 years old and male patients were more prevalent than female patients (68.7% compared to 31.3%, respectively). The most common diseases present were pneumonia and lung tuberculosis (55.3% and 39.3%, respectively). Hypoxemic respiratory failure occurred in 46% of the patients, while 54% had acute hypercapnic respiratory failure. Respiratory failure appeared more in acute onset (66% compared to 34% in chronic onset). Fifty-one patients (34%) were treated with invasive mechanical ventilation and 15.7% of them acquired nosocomial sepsis. Intrahospital mortality rate was 53.3%, and higher death risk was found in patients with mediastinal tumor (OR 1.93; 1.65-2.26; p=0.033), chronic kidney disease (OR 1.74; 1.31-2.31; p=0.037), and invasive mechanical ventilation (OR 1.75; 1.32-2.32; p=0). Conclusions. ARF was related to both respiratory and non-respiratory diseases. ARF cases in our hospital were predominantly pneumonia, hypercapnic type and acute onset. There was a significant mortality risk in patients with mediastinal tumor, chronic kidney disease (CKD) and invasive mechanical ventilation use.

Original languageEnglish
Pages (from-to)77-81
Number of pages5
JournalPneumologia
Volume67
Issue number2
Publication statusPublished - 1 Jan 2018

Keywords

  • Acute respiratory failure
  • Characteristics outcome

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