TY - JOUR
T1 - Channelized Hotelling observer assessing microcalcification detectability on 2D mammography
T2 - 18th Asia-Oceania Congress of Medical Physics, AOCMP 2018 and 16th South-East Asia Congress of Medical Physics, SEACOMP 2018
AU - Wigati, K. T.
AU - Vancoillie, L.
AU - Salomon, E.
AU - Zhang, G.
AU - Cockmartin, L.
AU - Marshall, N.
AU - Bosmans, H.
AU - Soejoko, D. S.
AU - Bliznakova, K.
AU - Petrov, D.
N1 - Funding Information:
This work is part of project on “CHO Model Observer Workshop” held in Leuven 2018, funded by MaXIMA project (a European Union’s Horizon 2020 research and innovation program), and P3-Stroke (a European Union Horizon2020 EIT Health project). The authors would also like to acknowledge Janne Vignero and Michiel Dehairs for participating in the human observer study.
Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2019/6/6
Y1 - 2019/6/6
N2 - This work was aimed to assess the detectability of microcalcifications as a function of tube voltage in 2D mammography using an in-house developed Channelized Hotelling Observer (CHO). The images of a 3D structured phantom, containing acrylic beads of different diameters in water and inserted signals (microcalcifications, spiculated and non-spiculated mass models) were assessed. Images had been acquired on a Siemens Mammomat Inspiration system at 5 different tube voltage levels (28-32 kVp) under AEC setting. The detectability of microcalcifications was analyzed in terms of percentage correctly detected signals (PC) as well as diameter threshold (dtr), using the CHO and human observers. Two Laguerre-Gauss and 8 Gabor channels were included in the two-layers CHO. The model and human observer results were retrieved from a 4-alternative forced choice (4-AFC) study. At 28 kVp and 32 kVp, the diameter thresholds dtr of microcalcifications together with their 95% confidence intervals (CI95) were 0.114 [0.110-0.118] mm and 0.119 [0.116-0.122] mm for the CHO, and 0.110 [0.093-0.127] mm and 0.123 [0.111-0.134] mm for the human observers. The Pearson correlation (r) between the PC values of model and human observer was more than 0.934. The in-house developed CHO and the human observer scores correlated very well for the application on 2D digital mammography acquired with different tube voltages. The overlapping range of CI95 of the dtr for the tested kVp shows that the tube voltage setting does not significantly affect the detectability of microcalcifications neither by the CHO nor by the human observers.
AB - This work was aimed to assess the detectability of microcalcifications as a function of tube voltage in 2D mammography using an in-house developed Channelized Hotelling Observer (CHO). The images of a 3D structured phantom, containing acrylic beads of different diameters in water and inserted signals (microcalcifications, spiculated and non-spiculated mass models) were assessed. Images had been acquired on a Siemens Mammomat Inspiration system at 5 different tube voltage levels (28-32 kVp) under AEC setting. The detectability of microcalcifications was analyzed in terms of percentage correctly detected signals (PC) as well as diameter threshold (dtr), using the CHO and human observers. Two Laguerre-Gauss and 8 Gabor channels were included in the two-layers CHO. The model and human observer results were retrieved from a 4-alternative forced choice (4-AFC) study. At 28 kVp and 32 kVp, the diameter thresholds dtr of microcalcifications together with their 95% confidence intervals (CI95) were 0.114 [0.110-0.118] mm and 0.119 [0.116-0.122] mm for the CHO, and 0.110 [0.093-0.127] mm and 0.123 [0.111-0.134] mm for the human observers. The Pearson correlation (r) between the PC values of model and human observer was more than 0.934. The in-house developed CHO and the human observer scores correlated very well for the application on 2D digital mammography acquired with different tube voltages. The overlapping range of CI95 of the dtr for the tested kVp shows that the tube voltage setting does not significantly affect the detectability of microcalcifications neither by the CHO nor by the human observers.
UR - http://www.scopus.com/inward/record.url?scp=85067692506&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/1248/1/012018
DO - 10.1088/1742-6596/1248/1/012018
M3 - Conference article
AN - SCOPUS:85067692506
SN - 1742-6588
VL - 1248
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
IS - 1
M1 - 012018
Y2 - 11 November 2018 through 14 November 2018
ER -