Challenges of vaccination information system implementation: A systematic literature review

Muhamad Adhytia Wana Putra Rahmadhan, Putu Wuri Handayani

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)


Globally, healthcare services have begun to show interest in switching from paper-based to electronic-based vaccination records through Vaccination Information Systems (VIS). VIS have been implemented in various countries, but the study on the challenges of implementing VIS in these countries is still limited. The challenges of implementing VIS need to be understood to become a subject of discussion and anticipation by other countries that are just starting to implement VIS. We analyzed 32 selected publications from 634 initially retrieved. Fourteen challenges were successfully identified when implementing VIS, including interoperability, data quality, security and privacy, standardization, usability, internet connectivity, infrastructure, workflow, funding, government regulations, awareness, skeptical response, computer literacy, and staff-related challenges. The challenges of interoperability and data quality were found to be the most widely discussed by previous studies. In addition to identifying the challenges, this study includes a series of solutions that can be applied to overcome each challenge.

Original languageEnglish
Article number2257054
JournalHuman Vaccines and Immunotherapeutics
Issue number2
Publication statusPublished - 2023


  • challenges
  • systematic literature review
  • vaccination
  • Vaccination information system
  • vaccination records


Dive into the research topics of 'Challenges of vaccination information system implementation: A systematic literature review'. Together they form a unique fingerprint.

Cite this