TY - JOUR
T1 - Challenges in Diagnosing Necrotizing Sarcoid Granulomatosis
T2 - The First Case Reported From Indonesia
AU - Singh, Gurmeet
AU - Karsono, Ramadhan
AU - Sjamsoe, Soedarman
AU - Triono, Muhammad Rizki
AU - Nora, Rina La Distia
AU - Felicia, Devi
AU - Gultom, Fajar Lamhot
AU - Ruslim, Daniel
AU - Sejati, Arif
AU - Gunarsa, Ralph Girson
AU - Pitoyo, Ceva Wicaksono
AU - Rumende, Cleopas Martin
N1 - Publisher Copyright:
Copyright © 2025 Gurmeet Singh et al. Case Reports in Medicine published by John Wiley & Sons Ltd.
PY - 2025
Y1 - 2025
N2 - Necrotizing sarcoid granulomatosis (NSG) is a rare disease characterized by granulomatous and necrotic features as well as vasculitis, and it primarily affects the lungs, with occasional extrapulmonary manifestations. The first documented case was in Jakarta, Indonesia. A 71-year-old male presented with prolonged fever, a neck mass, and multiple mediastinal lymphadenopathy. The disease was initially suspected as lung tuberculosis, but a surgical biopsy of the left thyroid lobe confirmed the NSG pattern. Treatment with oral prednisolone led to positive outcomes, as evidenced by radiological improvement at the 3-month follow-up. This case report aims to emphasize the challenges and the importance of clinician awareness in diagnosing NSG.
AB - Necrotizing sarcoid granulomatosis (NSG) is a rare disease characterized by granulomatous and necrotic features as well as vasculitis, and it primarily affects the lungs, with occasional extrapulmonary manifestations. The first documented case was in Jakarta, Indonesia. A 71-year-old male presented with prolonged fever, a neck mass, and multiple mediastinal lymphadenopathy. The disease was initially suspected as lung tuberculosis, but a surgical biopsy of the left thyroid lobe confirmed the NSG pattern. Treatment with oral prednisolone led to positive outcomes, as evidenced by radiological improvement at the 3-month follow-up. This case report aims to emphasize the challenges and the importance of clinician awareness in diagnosing NSG.
KW - extrapulmonary sarcoid
KW - malignancy
KW - necrotizing sarcoid granulomatosis
KW - thyroid
KW - tuberculosis
UR - http://www.scopus.com/inward/record.url?scp=105002634147&partnerID=8YFLogxK
U2 - 10.1155/carm/3219868
DO - 10.1155/carm/3219868
M3 - Article
AN - SCOPUS:105002634147
SN - 1687-9627
VL - 2025
JO - Case Reports in Medicine
JF - Case Reports in Medicine
IS - 1
M1 - 3219868
ER -
