TY - JOUR
T1 - Ceramic nanomaterials
T2 - Preparation and applications in osteoporosis and bone tissue regeneration
AU - John, Anish
AU - Shetty, Apurva M.
AU - Salian, Kshema
AU - Sequeria, Samantha Neha
AU - Sumukh, P. R.
AU - Sukmawati, Dewi
AU - Menon, Gowtham
AU - Abraham, Shajan
AU - Venkatesan, Jayachandran
AU - Narayanan, V. Anoop
N1 - Publisher Copyright:
© 2023, The Author(s), under exclusive licence to The Materials Research Society.
PY - 2023
Y1 - 2023
N2 - The lives and well-being of individuals have been greatly impacted by bone defects brought on by trauma, tumors, genetic disorders, osteoporosis, etc. Also, in the past few decades, the world's aging population has increased the need for nanotechnology to treat trauma-related bone diseases and tissue damage. To successfully imitate the structures seen in naturally occurring systems, nanoengineered systems can now do so. Hence, much focus and effort have been spent in the last decade on nanotechnology, especially nanomaterials. Ceramic nanomaterials have been widely used in tissue repair and engineering due to their high biocompatibility and reactivity. This review aims to identify and discuss the properties, applications in osteoporosis and bone tissue regeneration, mechanism of action, biocompatibility, drawbacks, and future scopes of a few ceramic nanomaterials, i.e., calcium phosphate, hydroxyapatite, mesoporous silica, and bioactive glass. Graphical Abstract: Images reproduced from sources: Adobe Stock, Wikimedia commons, Vecteezy, and iStock under creative commons (with free-to-reuse permission for noncommercial purposes).[Figure not available: see fulltext.]
AB - The lives and well-being of individuals have been greatly impacted by bone defects brought on by trauma, tumors, genetic disorders, osteoporosis, etc. Also, in the past few decades, the world's aging population has increased the need for nanotechnology to treat trauma-related bone diseases and tissue damage. To successfully imitate the structures seen in naturally occurring systems, nanoengineered systems can now do so. Hence, much focus and effort have been spent in the last decade on nanotechnology, especially nanomaterials. Ceramic nanomaterials have been widely used in tissue repair and engineering due to their high biocompatibility and reactivity. This review aims to identify and discuss the properties, applications in osteoporosis and bone tissue regeneration, mechanism of action, biocompatibility, drawbacks, and future scopes of a few ceramic nanomaterials, i.e., calcium phosphate, hydroxyapatite, mesoporous silica, and bioactive glass. Graphical Abstract: Images reproduced from sources: Adobe Stock, Wikimedia commons, Vecteezy, and iStock under creative commons (with free-to-reuse permission for noncommercial purposes).[Figure not available: see fulltext.]
KW - Bioglass and Osteoporosis
KW - Bone tissue regeneration
KW - Calcium Phosphate
KW - Hydroxyapatite
KW - Mesoporous Silica
UR - http://www.scopus.com/inward/record.url?scp=85165205186&partnerID=8YFLogxK
U2 - 10.1557/s43578-023-01101-x
DO - 10.1557/s43578-023-01101-x
M3 - Review article
AN - SCOPUS:85165205186
SN - 0884-2914
VL - 38
SP - 4023
EP - 4041
JO - Journal of Materials Research
JF - Journal of Materials Research
IS - 17
ER -