TY - JOUR
T1 - Carboxymethyl chitosan/amorphous calcium phosphate and dentin remineralization
AU - Santoso, Teguh
AU - Djauharie, Nila Kesuma
AU - Kamizar,
AU - Ahdi, Waviyatul
AU - Latief, Faurier Dzar Eljabbar
AU - Suprastiwi, Endang
N1 - Publisher Copyright:
© 2019 Journal of International Dental and Medical Research.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) is a non-collagen protein analogue that can replace the dentin matrix protein 1 (DMP1) function. The aim of this study was to analyze the effects of CMC/ACP in demineralized dentin. Two groups of four teeth with eight cavities were created. Group 1 teeth were filled with composite resin, whereas group 2 teeth were first applied with CMC/ACP followed by filling with composite resin. Then, all teeth were soaked in phosphate-buffered saline solution and placed in a shaking incubator at 37°C. On days 7 and 14 of incubation, the gray areas of the samples were analyzed using micro-computed tomography. The gray area of group 2 increased on both days 7 (35.171 ± 5.547) and 14 (43.281 ± 4.834), whereas those of group 1 decreased on day 14 (27.100). Thus, CMC/ACP may induce dentin remineralization.
AB - Carboxymethyl chitosan/amorphous calcium phosphate (CMC/ACP) is a non-collagen protein analogue that can replace the dentin matrix protein 1 (DMP1) function. The aim of this study was to analyze the effects of CMC/ACP in demineralized dentin. Two groups of four teeth with eight cavities were created. Group 1 teeth were filled with composite resin, whereas group 2 teeth were first applied with CMC/ACP followed by filling with composite resin. Then, all teeth were soaked in phosphate-buffered saline solution and placed in a shaking incubator at 37°C. On days 7 and 14 of incubation, the gray areas of the samples were analyzed using micro-computed tomography. The gray area of group 2 increased on both days 7 (35.171 ± 5.547) and 14 (43.281 ± 4.834), whereas those of group 1 decreased on day 14 (27.100). Thus, CMC/ACP may induce dentin remineralization.
KW - Amorphous calcium phosphate
KW - Carboxymethyl chitosan
KW - Dental caries
KW - Dentin
KW - Remineralization
UR - http://www.scopus.com/inward/record.url?scp=85069499552&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:85069499552
SN - 1309-100X
VL - 12
SP - 84
EP - 87
JO - Journal of International Dental and Medical Research
JF - Journal of International Dental and Medical Research
IS - 1
ER -