Can Near-Infrared Spectroscopy (NIRS) monitoring prevent post-operative cognitive dysfunction following open-heart surgery

Ratna Farida Soenarto, Jefferson Kasan Hidayat, Oryza Eureka, Aino Nindya Auerkari

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


Objective: This study aimed to evaluate the relationship between Post-operative Cognitive Dysfunction (POCD) and regional Oxygen saturation (rSOs) determined by NIRS monitoring during Open-heart surgery. Methods: This was a prospective cohort study of all patients about to undergo Open-heart surgery at Cipto Mangunkusumo National Referral Hospital, Jakarta. Subjects who fulfilled the selection criteria underwent cognitive assessment one day before the surgery. Basal rSO2was registered prior to anaesthetic induction, and this value was reported every 10 minutes throughout the procedure as the lowest rSO2and total desaturation (drop >20%) duration. On postoperative day 5, cognitive function was reassessed. We declared a drop in the cognitive function if the score dropped to >20% from the baseline in at least two cognitive tests. Results: The incidence of POCD was 51.7%. Basal rSO2values between POCD and non-POCD subjects were relatively similar. A significant difference was noted in the duration of total rSO2desaturation between the two groups. Total rSO2desaturation was longer in subjects with than without POCD. The ROC (receiver operating characteristic) curve showed a cut-off point of 20.5 minutes, with an AUC (area under curve) size of 126.5 minutes %. Conclusion: Absolute rSO2values did not correlate with POCD. However, a drop in rSO2value >20% from baseline may correlate with POCD. The use of NIRS in Open-heart surgery may, be beneficial for POCD prevention.

Original languageEnglish
Pages (from-to)S10-S13
JournalJournal of the Pakistan Medical Association
Issue number2
Publication statusPublished - Feb 2021


  • (JPMA 71: S-10 [Suppl. 2]; 2021)
  • Cardiac surgery
  • Cognitive dysfunction
  • Near-infrared spectroscopy


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