Background and Aims: Osteopenia and subsequent osteoporosis are complications faced by children living with lupus on steroid therapy. Calcium and vitamin D have been embedded in the management protocol early in therapy. AimÂ To evaluate calcium and vitamin D level in children with lupus. MethodsÂ Lupus patient recruited if their age 5â€“18 years old, on steroid therapy at least 5â€‰month. Lupus diagnosis, follow up record and SLEDAI score were retrieved from medical record. Subjects have DXA-scanning to determine bone density and plasma level for 25-hydroxyvitamin D and calcium at the latest visit. Daily intake of calcium and vitamin D was determined from 3â€‰day food diary.ResultsÂ There were 16 patient included, 14 were girls and average age 13.3 years. Duration of steroid use was 27.75+17.4â€‰month with the last SLEDAI score of mild and moderate flare on 9 subjects. Subjects received 400â€‰mg calcium and vitamin D3 200â€‰IU (5â€‰mcg) daily. Average Calcium intake was 587.58+213.29â€‰mg (RDA 1300â€‰mg/day) and vitamin D 2.9â€‰mcg daily(RDA 15â€‰mcg/day). Plasma level of 25-OHD was 19.3+5.4â€‰ng/ml (normal level 36â€“108) and calcium was 8.69+0.5â€‰mg/dl (normal level 8.5â€“10.2). DXA results showed 7 subjects with Z-score lumbal <âˆ’2.0 and mean Z-score âˆ’1.75+1.24. ConclusionsÂ Our paediatric Lupus patient showed low plasma level of calcium and vitamin D. Current supplementation should be increased 2 times to achieve relevant RDA and maintaining normal bone density.
|Publication status||Published - 2017|
|Event||12th International Congress on Systemic Lupus Erythematosus (LUPUS) and 7th Asian Congress on Autoimmunity (ACA) - AU, Melbourne, Australia|
Duration: 1 Jan 2017 → …
|Conference||12th International Congress on Systemic Lupus Erythematosus (LUPUS) and 7th Asian Congress on Autoimmunity (ACA)|
|Period||1/01/17 → …|