Bioactivities of Syzygium polyanthum (Wight) Walp leaf extract for decreasing diabetic risk

Indah Dwiatmi Dewijanti, Nina Artanti, Wibowo Mangunwardoyo, Muhammad Hanafi, Jamilah Abbas, Megawati Megawati, Minarti Minarti, Dian Musdalifah, Lia Meilawati

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

4 Citations (Scopus)

Abstract

Bay leaf (Syzygium polyanthum (Wight) Walp) is not only can be used as food seasoning and flavoring but also as medicine. Indonesian National Agency of Drug and Food Control established bay leaf as one of the nine major medicinal plants. The aim of this study was to conduct in vitro bioactivities analysis as antidiabetic, antioxidant and toxicity of bay leaf water extract. Bay leaf used in this study was collected from the gardens of research center for science and technology (Puspiptek) Serpong, Tangerang Selatan Indonesia, dried and extracted steeping in boiled water. Antidiabetic was measured using α-glucosidase inhibition method; antioxidant was measured using DPPH free radical flushing activity method; toxicity test was measured using Brine Shrimp Lethality Test (BSLT). The resulst showed that the decoction of bay leaves showed antidiabetic (41.4% inhibition of a-glucosidase) and antioxidant (49.4% scavenging of DPPH) activities at sample concentration of 50 μg/ml and very low toxic effect on brine shrimp larvae (LD50> 1000μg / mL). The results suggest that bay leaf water extract has potential to be used in development of functional drink to reduce diabetic risk.

Original languageEnglish
Title of host publicationProceeding of the 4th International Symposium on Applied Chemistry, ISAC 2018
EditorsMuhammad Arifuddin Fitriady, Siti Nurul Aisyiyah Jenie, Adid Adep Dwiatmoko
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735417441
DOIs
Publication statusPublished - 7 Nov 2018
Event4th International Symposium on Applied Chemistry, ISAC 2018 - Banten, Indonesia
Duration: 1 Nov 20182 Nov 2018

Publication series

NameAIP Conference Proceedings
Volume2024
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference4th International Symposium on Applied Chemistry, ISAC 2018
Country/TerritoryIndonesia
CityBanten
Period1/11/182/11/18

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