TY - GEN
T1 - Bioactivities of Salam leaf (Syzygium polyanthum (Wight) Walp)
AU - Dewijanti, I. D.
AU - Mangunwardoyo, W.
AU - Artanti, N.
AU - Hanafi, M.
N1 - Funding Information:
This research is funded by "INSINAS FLAGSHIP" Development of Functional Food Based on Local Resource” from Ministry of Research, Technology and Higher Education Republic of Indonesia 2018 fiscal year for Research Centre for Chemistry-LIPI.
Publisher Copyright:
© 2019 Author(s).
PY - 2019/11/4
Y1 - 2019/11/4
N2 - Plants are source of medicinal compounds. Salam leaf or Indonesian bay leaf (Syzygium polyanthum (Wight) Walp) from the family of Myrtaceae are widely used as herbs and spices for cooking (culinary) and as traditional medicine for diabetes, diarrhea, and hypertension. Indonesian bay leaf contains many compounds including essential oils, tannins, and flavonoids. In this study, 70 % and 96 % ethanol extracts of bay leaf obtained from the garden in Research Center for Science and Technology (PUSPIPTEK), Serpong, Tangerang Selatan, Indonesia were tested in vitro according to α-glucosidase inhibition method to determine antidiabetic activity and to scavenge DPPH free radicals in order to determine antioxidant activity and toxicity on Brine Shrimp Lethality Test (BSLT). The results showed that extraction of Indonesian bay leaf by using 70 % and 96 % ethanol extracts have anti diabetic activity (97.37 % and 95.51 % α-glucosidase inhibition) and antioxidants activities (89.66 % and 69.18 % DPPH inhibition), respectively and have very low toxic effects on brine shrimp larvae (LD50 > 1,000 μg/mL).
AB - Plants are source of medicinal compounds. Salam leaf or Indonesian bay leaf (Syzygium polyanthum (Wight) Walp) from the family of Myrtaceae are widely used as herbs and spices for cooking (culinary) and as traditional medicine for diabetes, diarrhea, and hypertension. Indonesian bay leaf contains many compounds including essential oils, tannins, and flavonoids. In this study, 70 % and 96 % ethanol extracts of bay leaf obtained from the garden in Research Center for Science and Technology (PUSPIPTEK), Serpong, Tangerang Selatan, Indonesia were tested in vitro according to α-glucosidase inhibition method to determine antidiabetic activity and to scavenge DPPH free radicals in order to determine antioxidant activity and toxicity on Brine Shrimp Lethality Test (BSLT). The results showed that extraction of Indonesian bay leaf by using 70 % and 96 % ethanol extracts have anti diabetic activity (97.37 % and 95.51 % α-glucosidase inhibition) and antioxidants activities (89.66 % and 69.18 % DPPH inhibition), respectively and have very low toxic effects on brine shrimp larvae (LD50 > 1,000 μg/mL).
KW - Bay leaf (Syzygium polyanthum (Wight) Walp.)
KW - bioactivities
KW - DPPH
UR - http://www.scopus.com/inward/record.url?scp=85075032587&partnerID=8YFLogxK
U2 - 10.1063/1.5132499
DO - 10.1063/1.5132499
M3 - Conference contribution
AN - SCOPUS:85075032587
T3 - AIP Conference Proceedings
BT - Proceedings of the 4th International Symposium on Current Progress in Mathematics and Sciences, ISCPMS 2018
A2 - Mart, Terry
A2 - Triyono, Djoko
A2 - Anggraningrum, Ivandini T.
PB - American Institute of Physics Inc.
T2 - 4th International Symposium on Current Progress in Mathematics and Sciences 2018, ISCPMS 2018
Y2 - 30 October 2018 through 31 October 2018
ER -
