Bioactive constituents of Garcinia porrecta and G. parvifolia grown in Indonesia

Leonardus B S Kardono, Muhammad Hanafi, Gatot Sherley, Soleh Kosela, Leslie J. Harrison

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

A new xanthone, porxanthone A (1) and one porlanosterol (2) were isolated; and three known xanthones, dulxanthone E (3), dulxanthone F (4), dulxanthone G (5) from G. porrecta, whereas two known xanthones, parvixanthone A (6) and rubraxanthone (7), were isolated from G. parvifolia. The structures of these compounds were determined by spectroscopic data analysis. The results of cytotoxicity evaluation showed that (3), (4), (5), (6), (7) were inhibitory to L1210 cells, with IC 50 values in the range of 3 to 8 μg mL -1.

Original languageEnglish
Pages (from-to)483-486
Number of pages4
JournalPakistan Journal of Biological Sciences
Volume9
Issue number3
DOIs
Publication statusPublished - 1 Mar 2006

Keywords

  • Cytotoxic
  • G. parvifolia
  • Garcinia porrecta
  • Lanosterol
  • Porxanthone

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