TY - JOUR
T1 - Bioactive constituents of Garcinia porrecta and G. parvifolia grown in Indonesia
AU - Kardono, Leonardus B S
AU - Hanafi, Muhammad
AU - Sherley, Gatot
AU - Kosela, Soleh
AU - Harrison, Leslie J.
PY - 2006/3
Y1 - 2006/3
N2 - A new xanthone, porxanthone A (1) and one porlanosterol (2) were isolated; and three known xanthones, dulxanthone E (3), dulxanthone F (4), dulxanthone G (5) from G. porrecta, whereas two known xanthones, parvixanthone A (6) and rubraxanthone (7), were isolated from G. parvifolia. The structures of these compounds were determined by spectroscopic data analysis. The results of cytotoxicity evaluation showed that (3), (4), (5), (6), (7) were inhibitory to L1210 cells, with IC 50 values in the range of 3 to 8 μg mL -1.
AB - A new xanthone, porxanthone A (1) and one porlanosterol (2) were isolated; and three known xanthones, dulxanthone E (3), dulxanthone F (4), dulxanthone G (5) from G. porrecta, whereas two known xanthones, parvixanthone A (6) and rubraxanthone (7), were isolated from G. parvifolia. The structures of these compounds were determined by spectroscopic data analysis. The results of cytotoxicity evaluation showed that (3), (4), (5), (6), (7) were inhibitory to L1210 cells, with IC 50 values in the range of 3 to 8 μg mL -1.
KW - Cytotoxic
KW - G. parvifolia
KW - Garcinia porrecta
KW - Lanosterol
KW - Porxanthone
UR - http://www.scopus.com/inward/record.url?scp=33646244041&partnerID=8YFLogxK
U2 - 10.3923/pjbs.2006.483.486
DO - 10.3923/pjbs.2006.483.486
M3 - Article
AN - SCOPUS:33646244041
SN - 1028-8880
VL - 9
SP - 483
EP - 486
JO - Pakistan Journal of Biological Sciences
JF - Pakistan Journal of Biological Sciences
IS - 3
ER -