Bilateral Orbital Proptosis and Corneal Ulcer in a Child with Acute Myeloid Leukemia

Made Susiyanti, Burhana Mawarasti, Sesaria Rizky Kumalasari

Research output: Contribution to journalArticlepeer-review


A 5-year-old girl had a 2-week history of protruding bilateral eye with blurred vision. The patient had a history of low-grade fever. Bilateral proptosis with a markedly severe protrusion of the conjunctival palpebral and infraorbital tissues was observed. A more pronounced proptosis occurred on the left eye. Lagophthalmos and corneal defects were found in the left eye. Laboratory tests revealed anemia, hyperleukocytosis, and thrombocytopenia. A confirmed diagnosis of acute myeloid leukemia-M2 was established from bone marrow aspiration. The patient was treated with standard multiagent chemotherapy and topical antibiotic eyedrops. Proptosis had resolved in 4 months with residual corneal cicatrix in the left eye.

Original languageEnglish
Pages (from-to)191-195
Number of pages5
JournalCase Reports in Ophthalmology
Publication statusPublished - 17 Mar 2022


  • Bilateral orbital proptosis
  • Childhood acute myeloid leukemia
  • Corneal ulcer


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