Beta defensin polipeptida antimikroba dalam hubungannya dengan periodontitis kronis dan agresif

Periodontitis is an inflammatory disease that attacks the periodontium and the main factors causing the loss of teeth in the world. In Indonesia, periodontal disease ranks second after caries and still is a problem in the community. Defensins are key elements of the innate immune system and as a first defense for oral tissues and other organs. HBDs has been detected in the gingival epithelium, salivary glands and saliva and gingival crevicular fluid (GCF). Objective to know about the existence of the Human beta defensin antimicrobial peptides, especially Human beta defensin-1 and its influence on the development of chronic and aggressive periodontitis either. There is an antimicrobial peptide, known as Human beta defensin which is the body's defense mechanism against infection early, in which the function and influence is still much debated by researchers