Many chemical accidents occur in the laboratories including fire, toxic chemical spills, hazardous materials leakage, fatalities and adverse health effects involving the use of hazardous materials. This research investigates the implementation of Chemical Health, Safety and Security Program within the health faculties laboratories at Universitas Indonesia. The method used in this study employed a Chemical Health, Safety and Security Checklist developed from several references including the: American Chemical Society Safety Audit/Inspection Manual, American Chemical Society Security Vulnerability Checklist for Academic and Small Chemical Laboratory Facilities, and Universitas Indonesia (UI) procedures for laboratory safety, health and security inspections. Inspections and observations are conducted in fifty one laboratories which use chemicals within the health faculties at UI. Result suggested that several laboratories have implemented a good University standard for a laboratory chemical safety, health and security programs, while others needs improvement in particular parameters.