Background: Periodontal disease is a risk factor for coronary artery disease. Streptococcus sanguinis is a pioneer bacterium, which colonizes the tooth surface and causes periodontal disease. S. sanguinis is found in atherosclerotic plaques. Periodontitis increases risk of cardiovascular disease. S. sanguinis is linked to both diseases. Objective: To analyze the relationship between the salivary count of S. sanguinis and the periodontal status of patients with and without coronary heart disease (CHD). Material and Methods: The periodontal status (plaque index, papilla bleeding index, pocket depth) of 40 non-CHD patients (controls) and 66 CHD patients was evaluated. Saliva samples were collected, and a quantitative analysis of S. sanguinis was conducted using the real-time polymerase chain reaction (RT-PCR). Results: The S. sanguinis count differed in CHD patients and non-CHD patients. The S. sanguinis count of CHD patients was not associated with the plaque index, papilla bleeding index, or pocket depth. Conclusion: The S. sanguinis count of CHD patients was lower than that of non-CHD patients. The S. sanguinis count was not associated with the periodontal status of CHD patients.
|Number of pages||7|
|Journal||Journal of International Dental and Medical Research|
|Publication status||Published - 1 Jan 2017|
- Coronary heart disease
- Periodontal status
- Streptococcus sanguinis