Association obesity ang negative Acid-fast bacilli among pulmonari tuberculosis Patients with type 2 diabetes mellitus

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Abstract

Obesity is known as protective factors of pulmonary tuberculosis (PTB) in non-diabetes mellitus population. However, it’s effect on PTB in type 2 diabetes mellitus (T2DM) patient is unclear. The study aims to determine the association between obesity and PTB in patient with T2DM. A crosssectional study was held in in-patient, The Department of Internal Medicine, Fatmawati General Hospital from January 2015 to December 2017. This study includes patient with T2DM who had been diagnosed with PTB and age > 18 years old. In this study negative Acid-fast-bacilli (AFB) founding defined as patient’s sputum is negative by smear microscopy, while obesity define as body mass index > 24.9 kg/m2. From 363 PTB patient with T2DM, 22.59% were obese. Results showed that prevalence of negative AFB founding in PTB patients with T2DM was 81.82% and it was solely associated with obesity (p:0.002, OR=6.36, 95%CI 1.9-21). Obese patients were likely to have negative AFB founding. It suggested that diagnosing PTB in patient with T2DM and obese can’t be solely based on bacteriological confirmation
Original languageEnglish
JournalJurnal Epidemiologi Kesehatan Indonesia
Publication statusPublished - 2020

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