Association between maternal exposure to arsenic by drinking water during pregnancy and risk of preterm birth: a systematic review and meta-analysis

Ria Margiana; Shadia Hamoud Alshahrani; Dilrabo Kayumova; Ahmed Hussien Radie Alawadi; Ahmed Hjazi; Ali Alsalamy; Qutaiba A. Qasim; Ashima Juyal; Nazila Garousi

doi:10.1080/09603123.2023.2280155

Association between maternal exposure to arsenic by drinking water during pregnancy and risk of preterm birth: a systematic review and meta-analysis

Ria Margiana, Shadia Hamoud Alshahrani, Dilrabo Kayumova, Ahmed Hussien Radie Alawadi, Ahmed Hjazi, Ali Alsalamy, Qutaiba A. Qasim, Ashima Juyal, Nazila Garousi

Department of Anatomy Pre Clinic

Research output: Contribution to journal › Review article › peer-review

Abstract

The relation of exposure to arsenic in drinking water during pregnancy to the risk of preterm birth (PTB) was contradictory. This meta-analysis aimed to examine the association between drinking water arsenic and PTB. A systematic search in PubMed and Scopus was performed to achieve all relevant studies. Odds ratios (OR) and 95% confidence intervals (CI) were used to pool data using the random-effect models. Overall, 11 studies with a total sample size of 3,404,189 participants were included in the meta-analysis. Arsenic exposure through drinking water during pregnancy was related to an increased risk of PTB (OR = 1.06; 95%CI = 1.01–1.10 for highest versus lowest category of arsenic), with significant heterogeneity across the studies (I² = 84.8%, P = 0.001). This finding was supported by cohort studies (OR = 1.05; 95%CI = 1.01–1.10). This meta-analysis proposes that higher arsenic exposure in drinking water may be a risk factor for PTB.

Original language	English
Pages (from-to)	2947-2956
Number of pages	10
Journal	International Journal of Environmental Health Research
Volume	34
Issue number	8
DOIs	https://doi.org/10.1080/09603123.2023.2280155
Publication status	Published - 2024

Keywords

Arsenic
meta-analysis
pregnancy
preterm birth
water

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1080/09603123.2023.2280155

Cite this

Margiana, R., Hamoud Alshahrani, S., Kayumova, D., Hussien Radie Alawadi, A., Hjazi, A., Alsalamy, A., Qasim, Q. A., Juyal, A., & Garousi, N. (2024). Association between maternal exposure to arsenic by drinking water during pregnancy and risk of preterm birth: a systematic review and meta-analysis. International Journal of Environmental Health Research, 34(8), 2947-2956. https://doi.org/10.1080/09603123.2023.2280155

@article{aadc06c1e20048719938b7c52ef7f16a,

title = "Association between maternal exposure to arsenic by drinking water during pregnancy and risk of preterm birth: a systematic review and meta-analysis",

abstract = "The relation of exposure to arsenic in drinking water during pregnancy to the risk of preterm birth (PTB) was contradictory. This meta-analysis aimed to examine the association between drinking water arsenic and PTB. A systematic search in PubMed and Scopus was performed to achieve all relevant studies. Odds ratios (OR) and 95% confidence intervals (CI) were used to pool data using the random-effect models. Overall, 11 studies with a total sample size of 3,404,189 participants were included in the meta-analysis. Arsenic exposure through drinking water during pregnancy was related to an increased risk of PTB (OR = 1.06; 95%CI = 1.01–1.10 for highest versus lowest category of arsenic), with significant heterogeneity across the studies (I2 = 84.8%, P = 0.001). This finding was supported by cohort studies (OR = 1.05; 95%CI = 1.01–1.10). This meta-analysis proposes that higher arsenic exposure in drinking water may be a risk factor for PTB.",

keywords = "Arsenic, meta-analysis, pregnancy, preterm birth, water",

author = "Ria Margiana and {Hamoud Alshahrani}, Shadia and Dilrabo Kayumova and {Hussien Radie Alawadi}, Ahmed and Ahmed Hjazi and Ali Alsalamy and Qasim, {Qutaiba A.} and Ashima Juyal and Nazila Garousi",

note = "Publisher Copyright: {\textcopyright} 2023 Informa UK Limited, trading as Taylor & Francis Group.",

year = "2024",

doi = "10.1080/09603123.2023.2280155",

language = "English",

volume = "34",

pages = "2947--2956",

journal = "International Journal of Environmental Health Research",

issn = "0960-3123",

publisher = "Taylor and Francis Ltd.",

number = "8",

}

Margiana, R, Hamoud Alshahrani, S, Kayumova, D, Hussien Radie Alawadi, A, Hjazi, A, Alsalamy, A, Qasim, QA, Juyal, A & Garousi, N 2024, 'Association between maternal exposure to arsenic by drinking water during pregnancy and risk of preterm birth: a systematic review and meta-analysis', International Journal of Environmental Health Research, vol. 34, no. 8, pp. 2947-2956. https://doi.org/10.1080/09603123.2023.2280155

Association between maternal exposure to arsenic by drinking water during pregnancy and risk of preterm birth: a systematic review and meta-analysis. / Margiana, Ria; Hamoud Alshahrani, Shadia; Kayumova, Dilrabo et al.
In: International Journal of Environmental Health Research, Vol. 34, No. 8, 2024, p. 2947-2956.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Association between maternal exposure to arsenic by drinking water during pregnancy and risk of preterm birth

T2 - a systematic review and meta-analysis

AU - Margiana, Ria

AU - Hamoud Alshahrani, Shadia

AU - Kayumova, Dilrabo

AU - Hussien Radie Alawadi, Ahmed

AU - Hjazi, Ahmed

AU - Alsalamy, Ali

AU - Qasim, Qutaiba A.

AU - Juyal, Ashima

AU - Garousi, Nazila

PY - 2024

Y1 - 2024

N2 - The relation of exposure to arsenic in drinking water during pregnancy to the risk of preterm birth (PTB) was contradictory. This meta-analysis aimed to examine the association between drinking water arsenic and PTB. A systematic search in PubMed and Scopus was performed to achieve all relevant studies. Odds ratios (OR) and 95% confidence intervals (CI) were used to pool data using the random-effect models. Overall, 11 studies with a total sample size of 3,404,189 participants were included in the meta-analysis. Arsenic exposure through drinking water during pregnancy was related to an increased risk of PTB (OR = 1.06; 95%CI = 1.01–1.10 for highest versus lowest category of arsenic), with significant heterogeneity across the studies (I2 = 84.8%, P = 0.001). This finding was supported by cohort studies (OR = 1.05; 95%CI = 1.01–1.10). This meta-analysis proposes that higher arsenic exposure in drinking water may be a risk factor for PTB.

AB - The relation of exposure to arsenic in drinking water during pregnancy to the risk of preterm birth (PTB) was contradictory. This meta-analysis aimed to examine the association between drinking water arsenic and PTB. A systematic search in PubMed and Scopus was performed to achieve all relevant studies. Odds ratios (OR) and 95% confidence intervals (CI) were used to pool data using the random-effect models. Overall, 11 studies with a total sample size of 3,404,189 participants were included in the meta-analysis. Arsenic exposure through drinking water during pregnancy was related to an increased risk of PTB (OR = 1.06; 95%CI = 1.01–1.10 for highest versus lowest category of arsenic), with significant heterogeneity across the studies (I2 = 84.8%, P = 0.001). This finding was supported by cohort studies (OR = 1.05; 95%CI = 1.01–1.10). This meta-analysis proposes that higher arsenic exposure in drinking water may be a risk factor for PTB.

KW - Arsenic

KW - meta-analysis

KW - pregnancy

KW - preterm birth

KW - water

UR - http://www.scopus.com/inward/record.url?scp=85176942900&partnerID=8YFLogxK

U2 - 10.1080/09603123.2023.2280155

DO - 10.1080/09603123.2023.2280155

M3 - Review article

AN - SCOPUS:85176942900

SN - 0960-3123

VL - 34

SP - 2947

EP - 2956

JO - International Journal of Environmental Health Research

JF - International Journal of Environmental Health Research

IS - 8

ER -

Association between maternal exposure to arsenic by drinking water during pregnancy and risk of preterm birth: a systematic review and meta-analysis

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this