TY - JOUR
T1 - Association between laryngopharyngeal reflux and obstructive sleep apnea in adults
AU - Tamin, Susyana
AU - Siregar, Dumasari
AU - Hutauruk, Syahrial Marsinta
AU - Restuti, Ratna Dwi
AU - Rachmawati, Elvie Zulka Kautzia
AU - Bardosono, Saptawati
N1 - Publisher Copyright:
© 2022 PeerJ Inc.. All rights reserved.
PY - 2022
Y1 - 2022
N2 - Background. Obstructive sleep apnea syndrome (OSAS) and laryngopharyngeal reflux (LPR) have been found to coexist in the population. OSAS and LPR also share obesity as an important risk factor. However, the relationship between LPR and OSAS remains unclear. This study aimed to correlate LPR as measured by the Reflux Symptom Index (RSI) and the Reflux Finding Score (RFS) with OSAS. Methods. This cross-sectional study included sixty-four subjects who underwent anamnesis to complete the RSI and the Epworth Sleeping Scale (ESS). The subjects were then divided into the OSAS and non-OSAS groups based on the Apnea-Hypopnea Index (AHI) obtained through a polysomnography examination. Both groups underwent a flexible fiberoptic nasopharyngolaryngoscopy examination to determine the RFS. LPR was identified based on the RSI and RFS. Results. The mean BMI of the OSAS group significantly was higher than the non-OSAS group (p < 0:05). Most of the subjects in the OSAS group exhibited mild-moderate OSAS (AHI 10_29), and severe OSAS occurred in only seven subjects. The mean RSI and RFS values in the OSAS group did not differ significantly from the non-OSAS group (pD0:34 and pD0:36, respectively). The proportion of LPR between the mild- moderate OSAS group, the severe OSAS group, and the non-OSAS group did not differ significantly (pD1:00). RSI and RFS did not significantly correlate with AHI. Based on RSI, the proportion of LPR between the ESS (+) and ESS (-) groups did not significantly differ (adjusted p D 0:062). The proportion of LPR based on RFS was almost equal between the ESS (+) and ESS (-) groups (pD0:817). Conclusions. The BMI of the OSAS group was significantly higher than the non-OSAS group. There was no significant difference in RSI and RFS between the OSAS and non- OSAS groups. There was no significant correlation between RSI and AHI, or between RFS and AHI. There was no significant difference in the proportion of RSI between the ESS (+) and the ESS (-) groups.
AB - Background. Obstructive sleep apnea syndrome (OSAS) and laryngopharyngeal reflux (LPR) have been found to coexist in the population. OSAS and LPR also share obesity as an important risk factor. However, the relationship between LPR and OSAS remains unclear. This study aimed to correlate LPR as measured by the Reflux Symptom Index (RSI) and the Reflux Finding Score (RFS) with OSAS. Methods. This cross-sectional study included sixty-four subjects who underwent anamnesis to complete the RSI and the Epworth Sleeping Scale (ESS). The subjects were then divided into the OSAS and non-OSAS groups based on the Apnea-Hypopnea Index (AHI) obtained through a polysomnography examination. Both groups underwent a flexible fiberoptic nasopharyngolaryngoscopy examination to determine the RFS. LPR was identified based on the RSI and RFS. Results. The mean BMI of the OSAS group significantly was higher than the non-OSAS group (p < 0:05). Most of the subjects in the OSAS group exhibited mild-moderate OSAS (AHI 10_29), and severe OSAS occurred in only seven subjects. The mean RSI and RFS values in the OSAS group did not differ significantly from the non-OSAS group (pD0:34 and pD0:36, respectively). The proportion of LPR between the mild- moderate OSAS group, the severe OSAS group, and the non-OSAS group did not differ significantly (pD1:00). RSI and RFS did not significantly correlate with AHI. Based on RSI, the proportion of LPR between the ESS (+) and ESS (-) groups did not significantly differ (adjusted p D 0:062). The proportion of LPR based on RFS was almost equal between the ESS (+) and ESS (-) groups (pD0:817). Conclusions. The BMI of the OSAS group was significantly higher than the non-OSAS group. There was no significant difference in RSI and RFS between the OSAS and non- OSAS groups. There was no significant correlation between RSI and AHI, or between RFS and AHI. There was no significant difference in the proportion of RSI between the ESS (+) and the ESS (-) groups.
KW - Laryngopharyngeal reflux
KW - LPR
KW - Obstructive sleep apnea
KW - OSA
UR - http://www.scopus.com/inward/record.url?scp=85130705839&partnerID=8YFLogxK
U2 - 10.7717/peerj.13303
DO - 10.7717/peerj.13303
M3 - Article
AN - SCOPUS:85130705839
SN - 2167-8359
VL - 10
JO - PeerJ
JF - PeerJ
M1 - e13303
ER -
