Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update

Yun Fan Liaw; Nancy Leung; Richard Guan; George K.K. Lau; Ismail Merican; Geoff McCaughan; Edward Gane; Jia Horng Kao; Masao Omata; B. A. Chutaputti; D. S. Chen; R. N. Chien; G. Cooksley; K. H. Han; T. Ichida; M. Y. Lai; Laurentius M. Adrianto Lesmana; T. Piratvisuth; S. K. Sarin; J. Sollano; D. J. Suh; G. B. Yao; C. T. Yeh; O. Yokosuka

doi:10.1111/j.1478-3231.2005.01134.x

Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update

Yun Fan Liaw, Nancy Leung, Richard Guan, George K.K. Lau, Ismail Merican, Geoff McCaughan, Edward Gane, Jia Horng Kao, Masao Omata, B. A. Chutaputti, D. S. Chen, R. N. Chien, G. Cooksley, K. H. Han, T. Ichida, M. Y. Lai, Laurentius M. Adrianto Lesmana, T. Piratvisuth, S. K. Sarin, J. SollanoD. J. Suh, G. B. Yao, C. T. Yeh, O. Yokosuka

Department of Internal Medicine

Research output: Contribution to journal › Review article › peer-review

331 Citations (Scopus)

Abstract

Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update. Methods: New data were presented, discussed and debated in an expert pre-meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL. Results: Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested. Conclusion: The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.

Original language	English
Pages (from-to)	472-489
Number of pages	18
Journal	Liver International
Volume	25
Issue number	3
DOIs	https://doi.org/10.1111/j.1478-3231.2005.01134.x
Publication status	Published - Jun 2005

Keywords

Adefovir
Chronic hepatitis B
Hepatic decompensation
Interferon
Lamivudine
Liver transplantation

Access to Document

10.1111/j.1478-3231.2005.01134.x

Cite this

Liaw, Y. F., Leung, N., Guan, R., Lau, G. K. K., Merican, I., McCaughan, G., Gane, E., Kao, J. H., Omata, M., Chutaputti, B. A., Chen, D. S., Chien, R. N., Cooksley, G., Han, K. H., Ichida, T., Lai, M. Y., Lesmana, L. M. A., Piratvisuth, T., Sarin, S. K., ... Yokosuka, O. (2005). Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update. Liver International, 25(3), 472-489. https://doi.org/10.1111/j.1478-3231.2005.01134.x

@article{cf597007b29d4cf096ea80f0140cc2fd,

title = "Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update",

abstract = "Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update. Methods: New data were presented, discussed and debated in an expert pre-meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL. Results: Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested. Conclusion: The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.",

keywords = "Adefovir, Chronic hepatitis B, Hepatic decompensation, Interferon, Lamivudine, Liver transplantation",

author = "Liaw, {Yun Fan} and Nancy Leung and Richard Guan and Lau, {George K.K.} and Ismail Merican and Geoff McCaughan and Edward Gane and Kao, {Jia Horng} and Masao Omata and Chutaputti, {B. A.} and Chen, {D. S.} and Chien, {R. N.} and G. Cooksley and Han, {K. H.} and T. Ichida and Lai, {M. Y.} and Lesmana, {Laurentius M. Adrianto} and T. Piratvisuth and Sarin, {S. K.} and J. Sollano and Suh, {D. J.} and Yao, {G. B.} and Yeh, {C. T.} and O. Yokosuka",

year = "2005",

month = jun,

doi = "10.1111/j.1478-3231.2005.01134.x",

language = "English",

volume = "25",

pages = "472--489",

journal = "Liver International",

issn = "1478-3223",

publisher = "Wiley-Blackwell Publishing Ltd",

number = "3",

}

Liaw, YF, Leung, N, Guan, R, Lau, GKK, Merican, I, McCaughan, G, Gane, E, Kao, JH, Omata, M, Chutaputti, BA, Chen, DS, Chien, RN, Cooksley, G, Han, KH, Ichida, T, Lai, MY, Lesmana, LMA, Piratvisuth, T, Sarin, SK, Sollano, J, Suh, DJ, Yao, GB, Yeh, CT & Yokosuka, O 2005, 'Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update', Liver International, vol. 25, no. 3, pp. 472-489. https://doi.org/10.1111/j.1478-3231.2005.01134.x

TY - JOUR

T1 - Asian-Pacific consensus statement on the management of chronic hepatitis B

T2 - A 2005 update

AU - Liaw, Yun Fan

AU - Leung, Nancy

AU - Guan, Richard

AU - Lau, George K.K.

AU - Merican, Ismail

AU - McCaughan, Geoff

AU - Gane, Edward

AU - Kao, Jia Horng

AU - Omata, Masao

AU - Chutaputti, B. A.

AU - Chen, D. S.

AU - Chien, R. N.

AU - Cooksley, G.

AU - Han, K. H.

AU - Ichida, T.

AU - Lai, M. Y.

AU - Lesmana, Laurentius M. Adrianto

AU - Piratvisuth, T.

AU - Sarin, S. K.

AU - Sollano, J.

AU - Suh, D. J.

AU - Yao, G. B.

AU - Yeh, C. T.

AU - Yokosuka, O.

PY - 2005/6

Y1 - 2005/6

N2 - Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update. Methods: New data were presented, discussed and debated in an expert pre-meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL. Results: Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested. Conclusion: The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.

AB - Background/Aims: A large amount of new data on the treatment of chronic hepatitis B has become available such that the 2003 consensus statement requires revision and update. Methods: New data were presented, discussed and debated in an expert pre-meeting to draft a revision. The revised contents were finalized after discussion in a general meeting of APASL. Results: Conceptual background, including the efficacy and safety profile of currently available and emerging drugs, was reviewed. Nineteen recommendations were formed and unresolved issues and areas for further study were suggested. Conclusion: The current therapy of chronic hepatitis B is modestly effective but not satisfactory. The development of new drugs and new strategies is required to further improve the outcomes of treatment.

KW - Adefovir

KW - Chronic hepatitis B

KW - Hepatic decompensation

KW - Interferon

KW - Lamivudine

KW - Liver transplantation

UR - http://www.scopus.com/inward/record.url?scp=20444363583&partnerID=8YFLogxK

U2 - 10.1111/j.1478-3231.2005.01134.x

DO - 10.1111/j.1478-3231.2005.01134.x

M3 - Review article

C2 - 15910483

AN - SCOPUS:20444363583

SN - 1478-3223

VL - 25

SP - 472

EP - 489

JO - Liver International

JF - Liver International

IS - 3

ER -

Asian-Pacific consensus statement on the management of chronic hepatitis B: A 2005 update

Abstract

Keywords

Access to Document

Other files and links

Fingerprint

Cite this