Application of ionic liquid as a green solvent for polyphenolics content extraction of peperomia pellucida (L) kunth herb

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Abstract

Objective: The aims of the study was to explore the application effect of ionic liquid as a green solvent in the polyphenolics content extraction from Peperomia pellucida (L.) Kunth herbs using 1-butyl-3-methyl imidazolium bromide ([BMIM]Br) and 1-butyl-3-methyl imidazolium chloride ([BMIM]Cl). Methods: The polyphenolics content extraction was performed by using the ionic liquid based microwave-assisted extraction (IL-MAE) method with some extraction parameters, including extraction time, microwave power, ratio liquid-solid, and ionic liquid concentration. The yields of total polyphenolic content were examined using a microplate reader 96 well method, and the extraction mechanism was analyzed using scanning electron microscopy (SEM). Results: The results showed that the effect of ionic liquid on the yield of total polyphenolics content, including 18.287 μg GAE/g (0.7 mol/l [BMIM]Cl concentration, 14 ml/l liquid-solid ratio, and 270 Watts microwave power for 10 minutes), and 15.734 μg GAE/g (0.7 mol/l [BMIM] Br concentration, 14 ml/l liquid-solid ratio, and 270 Watts microwave power for 15 minutes), whereas the SEM demonstrated the extraction mechanism with significant physical changes in matrix sample after treatment using different solvents. Conclusion: Application of green chemistry principles using an ionic liquid as a green solvent for the polyphenolic extraction of P. pellucida herbs to be rapid, easy, and efficient.

Original languageEnglish
Pages (from-to)486-490
Number of pages5
JournalJournal of Young Pharmacists
Volume9
Issue number4
DOIs
Publication statusPublished - 1 Oct 2017

Keywords

  • 1-butyl-3-methyl imidazolium bromide
  • 1-butyl-3-methyl imidazolium chloride
  • Ionic liquid-based microwave-assisted extraction
  • Peperomia pellucida (L.) Kunth
  • Total polyphenolic content

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