TY - GEN
T1 - Application of green extraction to increase the yield extract from Keji Beling (Strobilanthes crispus.) leaves as hypercholesterolemia medicine
AU - Angelina,
AU - Maidiono, Eldwin
AU - Putri, Naya Prakasita
AU - Arbianti, Rita
AU - Utami, Tania Surya
N1 - Publisher Copyright:
© 2019 Author(s).
PY - 2019/4/9
Y1 - 2019/4/9
N2 - Ultrasound-assisted enzymatic method of extraction (UAEE) is one of the green extraction methods that can be used for the extraction of active compounds from herbs. UAEE has advantages such as environmentally friendly extraction conditions, low investment costs and energy requirements are relatively small. The use of enzymes in this extraction method will catalyze the hydrolysis of cytoderms and glycoproteins, thus improving the release of bioactive compounds. This method can be used for the extraction of active compounds in medicinal plants, such as for the treatment of hypercholesterolemia. Phytosterols, that can be found in Keji Beling (Strobilanthes crispus.) leaves, when consumed will compete with cholesterol for absorption in the digestive system. The optimum extraction conditions with a maximum extraction yield of 39.99% are as follows: the concentration of ethanol is 50%, the amount of added enzyme is 70mg/g and the enzymatic hydrolysis time is 2h. Crude extract from keji beling is tested using Liebermann-Burchard (LB) reagent to identify phytosterols. The objective of this study is to evaluate the extraction of active compounds from keji beling herbs by using ultrasound-assisted enzymatic method.
AB - Ultrasound-assisted enzymatic method of extraction (UAEE) is one of the green extraction methods that can be used for the extraction of active compounds from herbs. UAEE has advantages such as environmentally friendly extraction conditions, low investment costs and energy requirements are relatively small. The use of enzymes in this extraction method will catalyze the hydrolysis of cytoderms and glycoproteins, thus improving the release of bioactive compounds. This method can be used for the extraction of active compounds in medicinal plants, such as for the treatment of hypercholesterolemia. Phytosterols, that can be found in Keji Beling (Strobilanthes crispus.) leaves, when consumed will compete with cholesterol for absorption in the digestive system. The optimum extraction conditions with a maximum extraction yield of 39.99% are as follows: the concentration of ethanol is 50%, the amount of added enzyme is 70mg/g and the enzymatic hydrolysis time is 2h. Crude extract from keji beling is tested using Liebermann-Burchard (LB) reagent to identify phytosterols. The objective of this study is to evaluate the extraction of active compounds from keji beling herbs by using ultrasound-assisted enzymatic method.
KW - green extraction
KW - hypercholesterolemia
KW - keji beling
KW - phytosterols, ultrasound-assisted enzymatic extraction
UR - http://www.scopus.com/inward/record.url?scp=85064805159&partnerID=8YFLogxK
U2 - 10.1063/1.5096730
DO - 10.1063/1.5096730
M3 - Conference contribution
AN - SCOPUS:85064805159
T3 - AIP Conference Proceedings
BT - 3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
A2 - Wulan, Praswasti P.D.K.
A2 - Gozan, Misri
A2 - Astutiningsih, Sotya
A2 - Ramahdita, Ghiska
A2 - Dhelika, Radon
A2 - Kreshanti, Prasetyanugraheni
PB - American Institute of Physics Inc.
T2 - 3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018
Y2 - 6 August 2018 through 8 August 2018
ER -