Application of green extraction to increase the yield extract from Keji Beling (Strobilanthes crispus.) leaves as hypercholesterolemia medicine

Angelina, Eldwin Maidiono, Naya Prakasita Putri, Rita Arbianti, Tania Surya Utami

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Ultrasound-assisted enzymatic method of extraction (UAEE) is one of the green extraction methods that can be used for the extraction of active compounds from herbs. UAEE has advantages such as environmentally friendly extraction conditions, low investment costs and energy requirements are relatively small. The use of enzymes in this extraction method will catalyze the hydrolysis of cytoderms and glycoproteins, thus improving the release of bioactive compounds. This method can be used for the extraction of active compounds in medicinal plants, such as for the treatment of hypercholesterolemia. Phytosterols, that can be found in Keji Beling (Strobilanthes crispus.) leaves, when consumed will compete with cholesterol for absorption in the digestive system. The optimum extraction conditions with a maximum extraction yield of 39.99% are as follows: the concentration of ethanol is 50%, the amount of added enzyme is 70mg/g and the enzymatic hydrolysis time is 2h. Crude extract from keji beling is tested using Liebermann-Burchard (LB) reagent to identify phytosterols. The objective of this study is to evaluate the extraction of active compounds from keji beling herbs by using ultrasound-assisted enzymatic method.

Original languageEnglish
Title of host publication3rd Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices
Subtitle of host publicationProceedings of the International Symposium of Biomedical Engineering, ISBE 2018
EditorsPraswasti P.D.K. Wulan, Misri Gozan, Sotya Astutiningsih, Ghiska Ramahdita, Radon Dhelika, Prasetyanugraheni Kreshanti
PublisherAmerican Institute of Physics Inc.
ISBN (Electronic)9780735418226
DOIs
Publication statusPublished - 9 Apr 2019
Event3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018 - Jakarta, Indonesia
Duration: 6 Aug 20188 Aug 2018

Publication series

NameAIP Conference Proceedings
Volume2092
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Conference

Conference3rd International Symposium of Biomedical Engineering''s Recent Progress in Biomaterials, Drugs Development, and Medical Devices, ISBE 2018
Country/TerritoryIndonesia
CityJakarta
Period6/08/188/08/18

Keywords

  • green extraction
  • hypercholesterolemia
  • keji beling
  • phytosterols, ultrasound-assisted enzymatic extraction

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