Application of green extraction methods to resveratrol extraction from peanut (Arachis Hypogaea L.) skin

Rezi Riadi Syahdi, Ratna Nadyana, Rizqi Heru Putri, Rosediana Santi, Abdul Mun’im

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)


Objective: This study compared the maceration extraction method with non-conventional extraction methods such as ultrasound-assisted extraction (UAE) and microwave-assisted extraction (MAE). Methods: To obtain resveratrol, various conditions were optimized: Solvent types (organic solvent [i.e. 70% ethanol] and green solvents [i.e. natural deep eutectic solvent (NADES) and ionic liquid (IL)]) and extraction methods. The resveratrol content in the extracts was analyzed by high-performance liquid chromatography. Results: It was determined that resveratrol extracted by UAE with NADES was composed of choline chloride-oxalic acid when the following conditions were used: The solid/liquid ratio of 1:20 (g/mL) and the extraction time of 15 min. These conditions produced higher resveratrol content (0.049 mg/g dry weight) than that using MAE with 70% ethanol (0.011 mg/g dry weight). However, the maceration method yielded the highest amount of resveratrol (0.221 mg/g dry weight), and MAE with IL produced the smallest amount of resveratrol (0.157 x 10-3 mg/g dry weight). Conclusion: Peanut skin extracted using the maceration method produced the highest amount of resveratrol compared to that using other methods.

Original languageEnglish
Pages (from-to)38-42
Number of pages5
JournalInternational Journal of Applied Pharmaceutics
Issue numberSpecial Issue 1
Publication statusPublished - Mar 2020


  • Arachis hypogaea
  • Extraction
  • Ionic liquid
  • Natural deep eutectic solvent
  • Resveratrol


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