Antioxidative compounds from crotalari sessiliflora

Abdul Mun’im, Osamu Negishi, Tetsuo Ozawa

Research output: Contribution to journalArticlepeer-review

59 Citations (Scopus)


Seven antioxidative compounds were isolated from the EtOAc extract of the aerial part of C. sessiliflora (Japanese name, tanukimame) by activity-guided fractionation with 2,2-diphenyl-1-picrylhydrazyl (DPPH). Among the isolated compounds, hydroxyeucomic acid showed the strongest free radical-scavenging activity, which was almost identical to that of epigallocatechin gallate, against DPPH. Orientin and isoorientin showed strong anti-peroxidative activities toward linoleic acid and protective effects against the bactericidal action of the tert-butyl peroxyl radical. Their activities were nearly equal to that of epigallocatechin gallate.

Original languageEnglish
Pages (from-to)410-414
Number of pages5
JournalBioscience, Biotechnology and Biochemistry
Issue number2
Publication statusPublished - 1 Jan 2003


  • Antioxidative compound
  • Crotalaria ses-silijíora
  • Free radical
  • Tert-butyl peroxyl radical


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