Antioxidative compounds from crotalari sessiliflora

Abdul Mun’im; Osamu Negishi; Tetsuo Ozawa

doi:10.1271/bbb.67.410

Antioxidative compounds from crotalari sessiliflora

Abdul Mun’im, Osamu Negishi, Tetsuo Ozawa

Department of Pharmacy

Research output: Contribution to journal › Article › peer-review

62 Citations (Scopus)

Abstract

Seven antioxidative compounds were isolated from the EtOAc extract of the aerial part of C. sessiliflora (Japanese name, tanukimame) by activity-guided fractionation with 2,2-diphenyl-1-picrylhydrazyl (DPPH). Among the isolated compounds, hydroxyeucomic acid showed the strongest free radical-scavenging activity, which was almost identical to that of epigallocatechin gallate, against DPPH. Orientin and isoorientin showed strong anti-peroxidative activities toward linoleic acid and protective effects against the bactericidal action of the tert-butyl peroxyl radical. Their activities were nearly equal to that of epigallocatechin gallate.

Original language	English
Pages (from-to)	410-414
Number of pages	5
Journal	Bioscience, Biotechnology and Biochemistry
Volume	67
Issue number	2
DOIs	https://doi.org/10.1271/bbb.67.410
Publication status	Published - 1 Jan 2003

Keywords

Antioxidative compound
Crotalaria ses-silijíora
Free radical
Tert-butyl peroxyl radical

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AB - Seven antioxidative compounds were isolated from the EtOAc extract of the aerial part of C. sessiliflora (Japanese name, tanukimame) by activity-guided fractionation with 2,2-diphenyl-1-picrylhydrazyl (DPPH). Among the isolated compounds, hydroxyeucomic acid showed the strongest free radical-scavenging activity, which was almost identical to that of epigallocatechin gallate, against DPPH. Orientin and isoorientin showed strong anti-peroxidative activities toward linoleic acid and protective effects against the bactericidal action of the tert-butyl peroxyl radical. Their activities were nearly equal to that of epigallocatechin gallate.

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Antioxidative compounds from crotalari sessiliflora

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