TY - JOUR
T1 - Antioxidative activity and phytochemistry profile of hibiscus sabdariffa herb extracts
AU - Fitrotunnisa, Qotrunnada
AU - Arsianti, Ade
AU - Tejaputri, Nadzila Anindya
AU - Qorina, Fona
N1 - Funding Information:
This article was presented at The 3rd International Conference and Exhibition on Indonesian Medical Education and Research Institute (ICE on IMERI 2018), Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia. We express our gratitude to Directorate of Research and Public Service (DRPM), University of Indonesia for the Publikasi Internasional Terindeks Scopus Untuk Tugas Akhir Mahasiswa (PITTA) research grant, fiscal year 2018. We thank the 3rd ICE on IMERI Committee who had supported the peer review and manuscript preparation before submitting to the journal.
Funding Information:
We express our gratitude to Directorate of Research and Public Service (DRPM), University of Indonesia for the Publikasi Internasional Terindeks Scopus Untuk Tugas Akhir Mahasiswa (PITTA) research grant, fiscal year 2018.
Publisher Copyright:
© 2019 The Authors. Published by Innovare Academic Sciences Pvt Ltd.
PY - 2019/11
Y1 - 2019/11
N2 - Objective: Hibiscus sabdariffa, known as Roselle, is a widely-cultivated herb in Indonesia and has been consumed as an herbal drink due to its medicinal properties. The purpose of this research is to identify the antioxidant activity and phytochemical profile of Hibiscus sabdariffa. Methods: The Hibiscus sabdariffa samples were extracted and macerated with three different organic solvents: Ethyl acetate, ethanol, and n-hexane. These extracts were then analyzed using thin layer chromatography (TLC) and phytochemical tests to identify the extracts’ secondary metabolites. The extracts’ antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Results: The phytochemistry tests were positive for glycosides, alkaloids, steroids, triterpenoids, tannins, and flavonoids. The TLC analysis revealed that the extracts containing two to three organic compounds. The ethanol Hibiscus sabdariffa extracts with an IC50 value 103.63 ppm showed stronger antioxidant activity than the ethyl acetate extract. Conclusion: Ethanol Hibiscus sabdariffa extracts may be a potential source of natural antioxidant.
AB - Objective: Hibiscus sabdariffa, known as Roselle, is a widely-cultivated herb in Indonesia and has been consumed as an herbal drink due to its medicinal properties. The purpose of this research is to identify the antioxidant activity and phytochemical profile of Hibiscus sabdariffa. Methods: The Hibiscus sabdariffa samples were extracted and macerated with three different organic solvents: Ethyl acetate, ethanol, and n-hexane. These extracts were then analyzed using thin layer chromatography (TLC) and phytochemical tests to identify the extracts’ secondary metabolites. The extracts’ antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method. Results: The phytochemistry tests were positive for glycosides, alkaloids, steroids, triterpenoids, tannins, and flavonoids. The TLC analysis revealed that the extracts containing two to three organic compounds. The ethanol Hibiscus sabdariffa extracts with an IC50 value 103.63 ppm showed stronger antioxidant activity than the ethyl acetate extract. Conclusion: Ethanol Hibiscus sabdariffa extracts may be a potential source of natural antioxidant.
KW - Antioxidant
KW - DPPH
KW - Hibiscus sabdariffa
KW - IC
KW - Phytochemical
UR - http://www.scopus.com/inward/record.url?scp=85077166581&partnerID=8YFLogxK
U2 - 10.22159/ijap.2019.v11s6.33532
DO - 10.22159/ijap.2019.v11s6.33532
M3 - Article
AN - SCOPUS:85077166581
SN - 0975-7058
VL - 11
SP - 29
EP - 32
JO - International Journal of Applied Pharmaceutics
JF - International Journal of Applied Pharmaceutics
IS - Special Issue 6
ER -