TY - JOUR
T1 - Antioxidant Activity of Gold Nanofilms Synthesized via Cyclic Voltammetry Technique
AU - Suliasih, Babay Asih
AU - Kurniawan, Dwi Giwang
AU - Angelina, Marissa
AU - Budi, Setia
AU - Katas, Haliza
N1 - Publisher Copyright:
© Published under licence by IOP Publishing Ltd.
PY - 2024
Y1 - 2024
N2 - Gold nanoparticles (AuNPs) have attracted much attention as one of the most effective agents with high catalytic activities for radical scavenging reactions. Many studies have investigated its antioxidant activity using various in vitro methods and have shown promising scavenging action. In this research, we demonstrated the synthesis of Au nanofilms (AuNFs) by cyclic voltammetry technique and evaluated for their antioxidant activity. The application of a range of voltage levels was utilized in the synthesis of AuNFs, and their antioxidant potential was subsequently assessed through in vitro 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. All AuNFs exhibited antioxidant activity which increased as the upper potential was reduced from 1,5 V to 0,75 V. The antioxidant activity of AuNFs was shown to increase gradually with longer incubation times before the DPPH assay, indicating a significant impact on their performance. The obtained inhibition percentage was ranging from 8,26% to 22,91%. The highest antioxidant activity could be achieved by synthesizing AuNFs using 0,75V of upper potential and incubating it for 90 minutes prior to DPPH assay. The variations in the applied potential influenced the morphological characteristics of AuNFs, leading to increased surface area, while the duration of incubation was found to enhance the efficacy of the scavenging reaction between the AuNFs and DPPH. In conclusion, this cyclic voltammetry technique was shown to successfully synthesize AuNFs with significant antioxidant activity.
AB - Gold nanoparticles (AuNPs) have attracted much attention as one of the most effective agents with high catalytic activities for radical scavenging reactions. Many studies have investigated its antioxidant activity using various in vitro methods and have shown promising scavenging action. In this research, we demonstrated the synthesis of Au nanofilms (AuNFs) by cyclic voltammetry technique and evaluated for their antioxidant activity. The application of a range of voltage levels was utilized in the synthesis of AuNFs, and their antioxidant potential was subsequently assessed through in vitro 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. All AuNFs exhibited antioxidant activity which increased as the upper potential was reduced from 1,5 V to 0,75 V. The antioxidant activity of AuNFs was shown to increase gradually with longer incubation times before the DPPH assay, indicating a significant impact on their performance. The obtained inhibition percentage was ranging from 8,26% to 22,91%. The highest antioxidant activity could be achieved by synthesizing AuNFs using 0,75V of upper potential and incubating it for 90 minutes prior to DPPH assay. The variations in the applied potential influenced the morphological characteristics of AuNFs, leading to increased surface area, while the duration of incubation was found to enhance the efficacy of the scavenging reaction between the AuNFs and DPPH. In conclusion, this cyclic voltammetry technique was shown to successfully synthesize AuNFs with significant antioxidant activity.
UR - http://www.scopus.com/inward/record.url?scp=85209064066&partnerID=8YFLogxK
U2 - 10.1088/1742-6596/2866/1/012009
DO - 10.1088/1742-6596/2866/1/012009
M3 - Conference article
AN - SCOPUS:85209064066
SN - 1742-6588
VL - 2866
JO - Journal of Physics: Conference Series
JF - Journal of Physics: Conference Series
IS - 1
M1 - 012009
T2 - 13th International Physics Seminar 2024, IPS 2024
Y2 - 1 June 2024
ER -