Antioxidant activity and inhibition of lipoxygenase activity ethanol extract of endosperm Arenga pinnata (Wurmb) merr

Berna Elya, Nuraini Puspitasari, Annisa Chairani Sudarmin

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective: The purpose of this study is to determine the antioxidant activity and the potential inhibition of lipoxygenase activity from sugar palm fruit. Methods: Antioxidant activity was evaluated by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) methods. Inhibition of lipoxygenase activity was performed in vitro. Sugar palm fruit was macerated with 95% ethanol. Results: The results showed that sugar palm fruit ethanol extract has antioxidant activity when using DPPH method with EC50 of 141.3929 µg/mL and the FRAP method with EC50 of 60.2083 µg/mL. Inhibition test of lipoxygenase activity showed inhibitory concentration 50% value of 71.376 µg/mL. Conclusions: Ethanol extract of endosperm Arenga pinnata has antioxidant activity, as determined using the DPPH method with EC50of 141.3929 µg/mL and the FRAP method with EC50 of 60.2083 µg/mL.

Original languageEnglish
Pages (from-to)76-80
Number of pages5
JournalAsian Journal of Pharmaceutical and Clinical Research
Volume10
Issue numberSpecial Issue October
DOIs
Publication statusPublished - 1 Oct 2017

Keywords

  • 2,2-Diphenyl-1-picrylhydrazyl
  • Arenga pinnata
  • Ferric reducing antioxidant power
  • Lipoxygenase
  • Sugar palm fruit

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