TY - JOUR
T1 - Antimicrobial activity of biosurfactant derived from Bacillus subtilis C19
AU - Yuliani, Hanif
AU - Perdani, Meka Saima
AU - Savitri, Imelda
AU - Manurung, Meilani
AU - Sahlan, Muhamad
AU - Wijanarko, Anondho
AU - Hermansyah, Heri
N1 - Publisher Copyright:
© 2018 The Authors. Published by Elsevier Ltd.
PY - 2018
Y1 - 2018
N2 - Bacillus subtilis produces lipopeptides biosurfactant that have a great potential for biotechnological and biopharmaceutical applications, and Surfactin is the most potent lipopeptide biosurfactant known. In this work, the lipopeptide biosurfactant produced by Indonesian marine bacteria, B. subtilis C19, was analyzed. After 300 h cultivation in defined medium, a crude biosurfactant concentration of 2 g/L was produced. Biosurfactant product characterization have revealed high stability product in the wide range variation of pH and salinity. The antimicrobial activity evaluation of biosurfactant against 6 human pathogenic microbes (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica Typhi, Listeria monocytogenes, and Candida albicans), demonstrated that biosurfactant produced by B. subtilis C19 have a specific antimicrobial activity. It could inhibit growth of C. albicans without inhibiting both gram-positive and gram-negative bacteria; therefore it could be promoted as antifungal active agent.
AB - Bacillus subtilis produces lipopeptides biosurfactant that have a great potential for biotechnological and biopharmaceutical applications, and Surfactin is the most potent lipopeptide biosurfactant known. In this work, the lipopeptide biosurfactant produced by Indonesian marine bacteria, B. subtilis C19, was analyzed. After 300 h cultivation in defined medium, a crude biosurfactant concentration of 2 g/L was produced. Biosurfactant product characterization have revealed high stability product in the wide range variation of pH and salinity. The antimicrobial activity evaluation of biosurfactant against 6 human pathogenic microbes (Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Salmonella enterica Typhi, Listeria monocytogenes, and Candida albicans), demonstrated that biosurfactant produced by B. subtilis C19 have a specific antimicrobial activity. It could inhibit growth of C. albicans without inhibiting both gram-positive and gram-negative bacteria; therefore it could be promoted as antifungal active agent.
KW - Antimicrobial
KW - Bacillus subtilis C19
KW - Biosurfactant
UR - http://www.scopus.com/inward/record.url?scp=85057401496&partnerID=8YFLogxK
U2 - 10.1016/j.egypro.2018.10.043
DO - 10.1016/j.egypro.2018.10.043
M3 - Conference article
AN - SCOPUS:85057401496
SN - 1876-6102
VL - 153
SP - 274
EP - 278
JO - Energy Procedia
JF - Energy Procedia
T2 - 5th International Conference on Energy and Environment Research, ICEER 2018
Y2 - 23 July 2018 through 27 July 2018
ER -
