TY - JOUR
T1 - Antifungal effectiveness of virgin coconut oil mousse against Candida albicans biofilm in children with early childhood caries
AU - Monica, Monica
AU - Fauziah, Eva
AU - Budiardjo, Sarworini Bagio
AU - Suharsini, Margaretha
AU - Sutadi, Heriandi
AU - Indiarti, Ike Siti
AU - Rizal, Mochamad Fahlevi
N1 - Publisher Copyright:
© 2018 Polish Dental Association.
PY - 2018
Y1 - 2018
N2 - Introduction: Early childhood caries is defined as the presence of one or more decayed teeth, missing (due to caries) or filled teeth surface in a child 71 months of age or younger. The presence of Candida albicans will increase caries pathogenicity. Objectives: The objective of this study was to analyze the antifungal effectiveness of virgin coconut oil (VCO) mousse against viability of C. albicans biofilm in children with early childhood caries. Material and methods: In this experimental laboratory study, C. albicans biofilm was exposed to three concentrations of VCO mousse, namely 0.8%, 8% and 80%. C. albicans biofilm viability was tested using crystal violet 0.5% and a colony forming unit assay. Statistical analysis was conducted using 1-way ANOVA. Results: VCO mousse 80% showed optical density and total viable colony count (CFU/ml) values significantly different compared to VCO mousse 0.8% and 8% (p < 0.05). Conclusions: VCO mousse exhibited antifungal effect against viability of C. albicans biofilm in children with early childhood caries.
AB - Introduction: Early childhood caries is defined as the presence of one or more decayed teeth, missing (due to caries) or filled teeth surface in a child 71 months of age or younger. The presence of Candida albicans will increase caries pathogenicity. Objectives: The objective of this study was to analyze the antifungal effectiveness of virgin coconut oil (VCO) mousse against viability of C. albicans biofilm in children with early childhood caries. Material and methods: In this experimental laboratory study, C. albicans biofilm was exposed to three concentrations of VCO mousse, namely 0.8%, 8% and 80%. C. albicans biofilm viability was tested using crystal violet 0.5% and a colony forming unit assay. Statistical analysis was conducted using 1-way ANOVA. Results: VCO mousse 80% showed optical density and total viable colony count (CFU/ml) values significantly different compared to VCO mousse 0.8% and 8% (p < 0.05). Conclusions: VCO mousse exhibited antifungal effect against viability of C. albicans biofilm in children with early childhood caries.
KW - Candida albicans
KW - Early childhood caries
KW - Virgin coconut oil
UR - http://www.scopus.com/inward/record.url?scp=85061534883&partnerID=8YFLogxK
U2 - 10.5114/jos.2018.80643
DO - 10.5114/jos.2018.80643
M3 - Article
AN - SCOPUS:85061534883
VL - 71
SP - 259
EP - 262
JO - Journal of Stomatology
JF - Journal of Stomatology
SN - 0011-4553
IS - 3
ER -