Antidiabetic activity and phytochemical constituents of syzygium cumini leave in Kadipaten, Central Java Indonesia, Indonesia

Zahra Fadhilah, Berna Elya, Heri Setiawan, Gumilar Adhi Nugroho, Febrika Wediasari, Eem Masaenah, Varda Arianti

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Ethnomedicaly, jamblang (java plum) has been used as antidiabetic treatment in Dayak Tribe. This study aims to evaluate the effectiveness and the safety of the jamblang leaf extract as an antidiabetic. Objective: Evaluate Effecticity of Syzigium cumini (java plum) as anti-diabetic herb. Method: The antidiabetic activity test, used an animal model which gaven food a high fat diet High Fat Diet (HFD) then it was induced with Streptozotocin injected intraperitoneally. The subjects used in the study were male rats (Ratus novergicus) Sprague-Dawley strain. Results: Oral administration of jamblang extract has anti hyperglycemic activity through decrease of fasting blood glucose point significantly (dose 1, 50mg/ Kg Bw p: <0 0001 dose 2 100 mg/Kg BW p: <0 0001)

Original languageEnglish
Pages (from-to)1502-1508
Number of pages7
JournalPharmacognosy Journal
Volume13
Issue number6
DOIs
Publication statusPublished - Dec 2021

Keywords

  • Anti-hyperglicemic
  • Fasting blood glucose
  • Syzigium cumini

Fingerprint

Dive into the research topics of 'Antidiabetic activity and phytochemical constituents of syzygium cumini leave in Kadipaten, Central Java Indonesia, Indonesia'. Together they form a unique fingerprint.

Cite this