Antidiabetic activity and phytochemical constituents of syzygium cumini leave in Kadipaten, Central Java Indonesia, Indonesia

Zahra Fadhilah; Berna Elya; Heri Setiawan; Gumilar Adhi Nugroho; Febrika Wediasari; Eem Masaenah; Varda Arianti

doi:10.5530/PJ.2021.13.191

Antidiabetic activity and phytochemical constituents of syzygium cumini leave in Kadipaten, Central Java Indonesia, Indonesia

Zahra Fadhilah, Berna Elya, Heri Setiawan, Gumilar Adhi Nugroho, Febrika Wediasari, Eem Masaenah, Varda Arianti

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Introduction: Ethnomedicaly, jamblang (java plum) has been used as antidiabetic treatment in Dayak Tribe. This study aims to evaluate the effectiveness and the safety of the jamblang leaf extract as an antidiabetic. Objective: Evaluate Effecticity of Syzigium cumini (java plum) as anti-diabetic herb. Method: The antidiabetic activity test, used an animal model which gaven food a high fat diet High Fat Diet (HFD) then it was induced with Streptozotocin injected intraperitoneally. The subjects used in the study were male rats (Ratus novergicus) Sprague-Dawley strain. Results: Oral administration of jamblang extract has anti hyperglycemic activity through decrease of fasting blood glucose point significantly (dose 1, 50mg/ Kg Bw p: <0 0001 dose 2 100 mg/Kg BW p: <0 0001)

Original language	English
Pages (from-to)	1502-1508
Number of pages	7
Journal	Pharmacognosy Journal
Volume	13
Issue number	6
DOIs	https://doi.org/10.5530/PJ.2021.13.191
Publication status	Published - Dec 2021

Keywords

Anti-hyperglicemic
Fasting blood glucose
Syzigium cumini

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.5530/PJ.2021.13.191

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title = "Antidiabetic activity and phytochemical constituents of syzygium cumini leave in Kadipaten, Central Java Indonesia, Indonesia",

abstract = "Introduction: Ethnomedicaly, jamblang (java plum) has been used as antidiabetic treatment in Dayak Tribe. This study aims to evaluate the effectiveness and the safety of the jamblang leaf extract as an antidiabetic. Objective: Evaluate Effecticity of Syzigium cumini (java plum) as anti-diabetic herb. Method: The antidiabetic activity test, used an animal model which gaven food a high fat diet High Fat Diet (HFD) then it was induced with Streptozotocin injected intraperitoneally. The subjects used in the study were male rats (Ratus novergicus) Sprague-Dawley strain. Results: Oral administration of jamblang extract has anti hyperglycemic activity through decrease of fasting blood glucose point significantly (dose 1, 50mg/ Kg Bw p: <0 0001 dose 2 100 mg/Kg BW p: <0 0001)",

keywords = "Anti-hyperglicemic, Fasting blood glucose, Syzigium cumini",

author = "Zahra Fadhilah and Berna Elya and Heri Setiawan and Nugroho, {Gumilar Adhi} and Febrika Wediasari and Eem Masaenah and Varda Arianti",

note = "Funding Information: We would like to acknowledge the financial assistance obtained from the {"}Grant PUTI (Scopus Indexed Publication Scholarship) University of Indonesia (Number: r: BA-1518/UN2.RST/PPM.00.03.01/2020) and Mark Herb, School of Pharmacy ITB for supporting standart solution for this research. Publisher Copyright: {\textcopyright} 2021 Phcogj.Com.",

year = "2021",

month = dec,

doi = "10.5530/PJ.2021.13.191",

language = "English",

volume = "13",

pages = "1502--1508",

journal = "Pharmacognosy Journal",

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TY - JOUR

T1 - Antidiabetic activity and phytochemical constituents of syzygium cumini leave in Kadipaten, Central Java Indonesia, Indonesia

AU - Fadhilah, Zahra

AU - Elya, Berna

AU - Setiawan, Heri

AU - Nugroho, Gumilar Adhi

AU - Wediasari, Febrika

AU - Masaenah, Eem

AU - Arianti, Varda

N1 - Funding Information: We would like to acknowledge the financial assistance obtained from the "Grant PUTI (Scopus Indexed Publication Scholarship) University of Indonesia (Number: r: BA-1518/UN2.RST/PPM.00.03.01/2020) and Mark Herb, School of Pharmacy ITB for supporting standart solution for this research. Publisher Copyright: © 2021 Phcogj.Com.

PY - 2021/12

Y1 - 2021/12

N2 - Introduction: Ethnomedicaly, jamblang (java plum) has been used as antidiabetic treatment in Dayak Tribe. This study aims to evaluate the effectiveness and the safety of the jamblang leaf extract as an antidiabetic. Objective: Evaluate Effecticity of Syzigium cumini (java plum) as anti-diabetic herb. Method: The antidiabetic activity test, used an animal model which gaven food a high fat diet High Fat Diet (HFD) then it was induced with Streptozotocin injected intraperitoneally. The subjects used in the study were male rats (Ratus novergicus) Sprague-Dawley strain. Results: Oral administration of jamblang extract has anti hyperglycemic activity through decrease of fasting blood glucose point significantly (dose 1, 50mg/ Kg Bw p: <0 0001 dose 2 100 mg/Kg BW p: <0 0001)

AB - Introduction: Ethnomedicaly, jamblang (java plum) has been used as antidiabetic treatment in Dayak Tribe. This study aims to evaluate the effectiveness and the safety of the jamblang leaf extract as an antidiabetic. Objective: Evaluate Effecticity of Syzigium cumini (java plum) as anti-diabetic herb. Method: The antidiabetic activity test, used an animal model which gaven food a high fat diet High Fat Diet (HFD) then it was induced with Streptozotocin injected intraperitoneally. The subjects used in the study were male rats (Ratus novergicus) Sprague-Dawley strain. Results: Oral administration of jamblang extract has anti hyperglycemic activity through decrease of fasting blood glucose point significantly (dose 1, 50mg/ Kg Bw p: <0 0001 dose 2 100 mg/Kg BW p: <0 0001)

KW - Anti-hyperglicemic

KW - Fasting blood glucose

KW - Syzigium cumini

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DO - 10.5530/PJ.2021.13.191

M3 - Article

AN - SCOPUS:85120331838

SN - 0975-3575

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SP - 1502

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ER -

Antidiabetic activity and phytochemical constituents of syzygium cumini leave in Kadipaten, Central Java Indonesia, Indonesia

Abstract

Keywords

UN SDGs

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