TY - JOUR
T1 - Antibacterial potential of Nicotiana tabacum L. var virginia pyrolysis extract against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa
AU - Fernanda, S. A.
AU - Amru, B. A.
AU - Rahmani, H. A.
AU - Gozan, M.
AU - Irsyad, N. S.
AU - Bahar, M.
AU - Puspita, O. S.
AU - Zulfa, F.
AU - Pramono, A.
N1 - Funding Information:
Funding: The works were financially supported by the Universitas Pembangunan Nasional Veteran Jakarta, Hibah Simlitabmas (Contract Nr. 001/UN.61.4/2020)
Publisher Copyright:
© 2021 Institute of Physics Publishing. All rights reserved.
PY - 2021/5/5
Y1 - 2021/5/5
N2 - Tobacco plants are one of the main trade commodities in Indonesia. At present, the main production of tobacco is cigarettes. However, tobacco has active antibacterial compounds, such as phenols, alkaloids, and essential oils. Therefore, tobacco can be used in the health sector. This study was conducted to determine the effectiveness of the pyrolysis extract of Nicotiana tabacum L. var Virginia in inhibiting Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. This study uses a true experimental research design with tobacco extract samples obtained by pyrolysis at concentrations of 20%, 40%, 60%, 80%, and 100%. The antibacterial test carried out was the Kirby-Bauer diffusion method on Mueller Hinton Agar (MHA) media. One-Way ANOVA test results with p <0.05 indicate the effectiveness of tobacco pyrolysis extract in inhibiting Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. The average yield of inhibition zones found in Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa were 6.35 mm, 5.9 mm, 3.97 mm, and 5.025 mm. From these results, Staphylococcus aureus bacteria became the most sensitive bacteria with Virginia tobacco pyrolysis extract.
AB - Tobacco plants are one of the main trade commodities in Indonesia. At present, the main production of tobacco is cigarettes. However, tobacco has active antibacterial compounds, such as phenols, alkaloids, and essential oils. Therefore, tobacco can be used in the health sector. This study was conducted to determine the effectiveness of the pyrolysis extract of Nicotiana tabacum L. var Virginia in inhibiting Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. This study uses a true experimental research design with tobacco extract samples obtained by pyrolysis at concentrations of 20%, 40%, 60%, 80%, and 100%. The antibacterial test carried out was the Kirby-Bauer diffusion method on Mueller Hinton Agar (MHA) media. One-Way ANOVA test results with p <0.05 indicate the effectiveness of tobacco pyrolysis extract in inhibiting Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. The average yield of inhibition zones found in Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa were 6.35 mm, 5.9 mm, 3.97 mm, and 5.025 mm. From these results, Staphylococcus aureus bacteria became the most sensitive bacteria with Virginia tobacco pyrolysis extract.
UR - http://www.scopus.com/inward/record.url?scp=85107154488&partnerID=8YFLogxK
U2 - 10.1088/1755-1315/755/1/012013
DO - 10.1088/1755-1315/755/1/012013
M3 - Conference article
AN - SCOPUS:85107154488
SN - 1755-1307
VL - 755
JO - IOP Conference Series: Earth and Environmental Science
JF - IOP Conference Series: Earth and Environmental Science
IS - 1
M1 - 012013
T2 - 1st Annual Conference on Health and Food Science Technology, ACHOST 2020
Y2 - 25 November 2020
ER -