Antibacterial potential of Nicotiana tabacum L. var virginia pyrolysis extract against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa

S. A. Fernanda, B. A. Amru, H. A. Rahmani, M. Gozan, N. S. Irsyad, M. Bahar, O. S. Puspita, F. Zulfa, A. Pramono

Research output: Contribution to journalConference articlepeer-review

Abstract

Tobacco plants are one of the main trade commodities in Indonesia. At present, the main production of tobacco is cigarettes. However, tobacco has active antibacterial compounds, such as phenols, alkaloids, and essential oils. Therefore, tobacco can be used in the health sector. This study was conducted to determine the effectiveness of the pyrolysis extract of Nicotiana tabacum L. var Virginia in inhibiting Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. This study uses a true experimental research design with tobacco extract samples obtained by pyrolysis at concentrations of 20%, 40%, 60%, 80%, and 100%. The antibacterial test carried out was the Kirby-Bauer diffusion method on Mueller Hinton Agar (MHA) media. One-Way ANOVA test results with p <0.05 indicate the effectiveness of tobacco pyrolysis extract in inhibiting Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa. The average yield of inhibition zones found in Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa were 6.35 mm, 5.9 mm, 3.97 mm, and 5.025 mm. From these results, Staphylococcus aureus bacteria became the most sensitive bacteria with Virginia tobacco pyrolysis extract.

Original languageEnglish
Article number012013
JournalIOP Conference Series: Earth and Environmental Science
Volume755
Issue number1
DOIs
Publication statusPublished - 5 May 2021
Event1st Annual Conference on Health and Food Science Technology, ACHOST 2020 - Yogyakarta, Indonesia
Duration: 25 Nov 2020 → …

Fingerprint

Dive into the research topics of 'Antibacterial potential of Nicotiana tabacum L. var virginia pyrolysis extract against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, and Pseudomonas aeruginosa'. Together they form a unique fingerprint.

Cite this