Antibacterial effect of java turmeric ethanol extract against dual-species streptococcus mutans and streptococcus sanguinis biofilm (In vitro)

Ajrina Busri, Ria Puspitawati, Sri Utami

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Objectives: The minimal bactericidal concentration (MBC) of Java turmeric (Curcuma xanthorrhiza Roxb.) ethanol extract is 25% against Streptococcus mutans and 15% against Streptococcus sanguinis as single species. This study aimed to examine the antibacterial effect of Java turmeric ethanol extract against S. mutans and S. sanguinis as dual-species. S. mutans and S. sanguinis compete against each other to obtain nutrients. Methods: The antibacterial effect of Java turmeric ethanol extract against dual-species Streptococcus in vitro was analyzed by measuring the growth of bacteria after exposure to the extract by counting colony formation and quantifying bacterial cell numbers using real-time polymerase chain reaction. Result: The MBC of Java turmeric ethanol extract against dual-species Streptococcus is 10%. S. sanguinis is more sensitive to the extract than S. mutans. Conclusions: The antibacterial effect of Java turmeric ethanol extract on S. mutans and S. sanguinis as single species differs from the effect on the bacteria as dual-species of Streptococcus.

Original languageEnglish
Pages (from-to)57-60
Number of pages4
JournalAsian Journal of Pharmaceutical and Clinical Research
Volume10
Issue numberSpecial Issue October
DOIs
Publication statusPublished - 1 Oct 2017

Keywords

  • Dual-species streptococcus
  • Java turmeric ethanol extract
  • Streptococcus mutans
  • Streptococcus sanguinis

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