Abstract
Objectives: The minimal bactericidal concentration (MBC) of Java turmeric (Curcuma xanthorrhiza Roxb.) ethanol extract is 25% against Streptococcus mutans and 15% against Streptococcus sanguinis as single species. This study aimed to examine the antibacterial effect of Java turmeric ethanol extract against S. mutans and S. sanguinis as dual-species. S. mutans and S. sanguinis compete against each other to obtain nutrients. Methods: The antibacterial effect of Java turmeric ethanol extract against dual-species Streptococcus in vitro was analyzed by measuring the growth of bacteria after exposure to the extract by counting colony formation and quantifying bacterial cell numbers using real-time polymerase chain reaction. Result: The MBC of Java turmeric ethanol extract against dual-species Streptococcus is 10%. S. sanguinis is more sensitive to the extract than S. mutans. Conclusions: The antibacterial effect of Java turmeric ethanol extract on S. mutans and S. sanguinis as single species differs from the effect on the bacteria as dual-species of Streptococcus.
| Original language | English |
|---|---|
| Pages (from-to) | 57-60 |
| Number of pages | 4 |
| Journal | Asian Journal of Pharmaceutical and Clinical Research |
| Volume | 10 |
| Issue number | Special Issue October |
| DOIs | |
| Publication status | Published - Oct 2017 |
Keywords
- Dual-species streptococcus
- Java turmeric ethanol extract
- Streptococcus mutans
- Streptococcus sanguinis