Antibacterial activity of silver nanoparticles on fixed retainer adhesive toward treponema denticola

Jessica Santoso, Maria Purbiati, Krisnawati

Research output: Contribution to journalArticle

Abstract

Objective: The objective of this study was to develop an antibacterial flowable composite containing silver nanoparticle (AgNP) for the prevention of periodontal disease in fixed retainers. Methods: About 1% AgNP was incorporated into a commercial composite (tetric flow). The experimental and control products were used to bond fixed retainers to 28 extracted mandibular first premolars. The samples were randomly divided into four groups (n=7): Premolar bonded with fiber-reinforced composites and tetric flow (F1); premolar bonded with fiber-reinforced composites and AgNP-enhanced tetric flow (F2); premolar bonded with multistranded wires (MW) and tetric flow (M1); and premolar bonded with MW and AgNP-enhanced tetric flow (M2). Each sample was submerged in a test tube containing bacterial Treponema denticola solution and was incubated for 24 h and 37°temperature. The bacterial colony in each group was counted and analyzed. Results: This study showed that there was significant difference of T. denticola colony count between groups with and without AgNP-enhanced composites in both types of retainers. Conclusion: AgNP-enhanced flowable composites reduce the bacteria T. denticola colony count and possibly inhibit periodontal disease.

Original languageEnglish
Pages (from-to)198-200
Number of pages3
JournalInternational Journal of Applied Pharmaceutics
Volume11
DOIs
Publication statusPublished - 1 Apr 2019

Keywords

  • Fixed retainer
  • Periodontal disease
  • Silver nanoparticle
  • Treponema denticola

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