@inproceedings{7d5f3cc0b4cd41f9b0074b75be53ca54,
title = "Anti-Cancer activity of Swietenia mahagoni seed extract in ethyl acetate-induced breast cancer cell T47D",
abstract = "Cytotoxicity of compounds and anticancer potential from Swietenia mahagoni in the ethyl acetate fraction have been analyzed as health or medicinal food. The study was examining cytotoxicity of active fraction from Swietenia mahagoni seed toward breast cancer T47D. Ethyl acetate fraction was fractionated used cromatography coloum with silica gel as the stationary phase and chloroform-ethyl acetate as the mobile phase and yielded 8 fractions. Determination of toxicity of compound has been conducted through Brine Shrimp Lethality Test. Evaluation of chemical compound was performed by phytochemical assay. Results showed that fraction 2 with LC50 74.30 ppm could inhibit the growth of T47D cell with IC50 of 49.12 ppm. Based on phytochemical assay, fraction 2 consists of alkaloid and steroid/triterpenoid.",
author = "D. Tohir and Wuyung, {P. E.} and R. Farida",
note = "Publisher Copyright: {\textcopyright} 2020 Author(s).; 8th International Conference of the Indonesian Chemical Society 2019, ICICS 2019 ; Conference date: 06-08-2019 Through 07-08-2019",
year = "2020",
month = jun,
day = "4",
doi = "10.1063/5.0005908",
language = "English",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Mohamad Rafi and Rudi Heryanto and Wahyuni, {Wulan Tri}",
booktitle = "8th International Conference of the Indonesian Chemical Society, ICICS 2019",
address = "United States",
}
