Annual risk of tuberculosis infection in West Sumatra Province, Indonesia

Adang Bachtiar, Tri Yunis Miko Wayhono, R. Machmud, Besral, Yudarini, C. Basri, F. Mehta, V. K. Chadha, F. Loprang, D. Manissero, K. R. Palupi, R. Jitendra

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13 Citations (Scopus)

Abstract

OBJECTIVE: To estimate the annual risk of tuberculosis infection (ARTI) among children attending elementary school Classes I-III in West Sumatra Province, Indonesia. METHODS: The survey was designed to estimate ARTI among children, irrespective of BCG scar status. Fieldwork was carried out in 72 schools selected by two-stage sampling. Children were administered 2 TU of purified protein derivative RT23 with Tween 80 intradermally on the mid-anterior aspect of the left forearm. The maximum transverse diameter of induration was measured at about 72 h. Analysis was carried out among 5653 satisfactorily test-read children aged 6-9 years. RESULTS: The estimation by mirror-image method among all children (without and with BCG scar) revealed an ARTI of between 1% and 1.3%. The estimated ARTIs among children without and with BCG scar varied between 0.8-1.3% and 0.9-1.4%, respectively, using the mirror-image method, anti-mode method and mixture model. CONCLUSION: Tuberculosis control efforts need to be intensified to reduce the risk of transmission of infection.

Original languageEnglish
Pages (from-to)255-261
Number of pages7
JournalInternational Journal of Tuberculosis and Lung Disease
Volume12
Issue number3
Publication statusPublished - 1 Mar 2008

Keywords

  • Annual risk
  • Indonesia
  • Infection
  • Tuberculin survey
  • Tuberculosis

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