ANGKA KEMATIAN PASIEN AIDS DENGAN INFEKSI OPORTUNISTIK OTAK DI RSCM

Introduction: Brain opportunistic infections is the most frequent AIDS complication in Neurology Ward in RSCM. However, the prevalence, mortality, and characteristic of the patients in the last three years were unknown.
Method: This was a prospective historical studi using secondary data from inpatient HIV/AIDS patients in RSCM from January 2007 until September 2010.
Results: 1637 inpatient HIV patients were found. Brain opportunistic infections were as much as 470 cases (28,7%). Mortality rate for brain opportunistic infections is 44,7%. Three most frequent cases were toxoplasma encephalitis (48,5%), followed by brain tuberculosis (44,7%), and cryptococcal meningitis (7,4%). Case fatality ratios based on the diagnosis, from the lowest were as follow: toxoplasma encephalitis 0,31, multiple infection 0,49, cryptococcal meningitis 0,51, brain tuberculosis 0,60, and nonspecific diagnosis 0,69.
Conclusion: Brain opportunistic infections have high mortality rate. Related variables were: decrease level of consciousness, nuchal rigidity, meningeal enhancement, hypoalbuminemia, co morbidity, diagnosis other than toxoplasma encephalitis, history of using intravenous drugs, and employment.