Andrographolide undergoes modification after illumination by blue laser in the presence of sodium bicarbonate

Andrianopsyah Mas Jaya Putra, Siti Rahmah Kurnia, Fathimah Nurmajdina Marjani, Teni Ernawati, Isnaeni Isnaeni, Puspa Dewi Narrij Lotulung, Andini Sundowo, Ernawati Simanjuntak, Megawati Megawati, Arry Yanuar, Chaidir Chaidir, Muhammad Hanafi

Research output: Contribution to journalArticlepeer-review

Abstract

Andrographolide is the marker compound of Andrographis paniculata (Kalmegh), a herb that constitutes many traditional Asian remedies. In the present photochemical approach to modify its 12-en-14-hydroxyl moiety into 13-enone, a methanol solution of andrographolide has been illuminated with blue laser for 6 hours in the presence of sodium bicarbonate. After the illumination, it has been discovered that the 12-en-14-hydroxyl moiety undergoes modification into the 11-enone.

Original languageEnglish
Pages (from-to)1384-1387
Number of pages4
JournalIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
Volume59 B
Issue number9
Publication statusPublished - Sep 2020

Keywords

  • Andrographolide
  • Blue laser
  • Illumination
  • Modification
  • Sodium bicarbonate

Fingerprint

Dive into the research topics of 'Andrographolide undergoes modification after illumination by blue laser in the presence of sodium bicarbonate'. Together they form a unique fingerprint.

Cite this