Analysis of tuberculosis treatment suitability and the drug supervisor’s role in a community health center in pademangan subdistrict, north jakarta

Citra Febriony, Purwantyastuti, Meanaldi Rasmin, Vivian Soetikno

Research output: Contribution to journalArticle

Abstract

Objective: Appropriate tuberculosis (TB) treatment guidelines are one of the many factors that influence the success of TB treatment. The patient’s drug supervisor is a functional role that is part of the directly observed treatment short course, a program to support the success of TB treatment. The aim of this study was to analyze the TB treatment suitability in a community health center and the benefit of treatment compliance supervision by the patient’s designated drug supervisor. Methods: We conducted a cross-sectional study in the Community Health Center of Pademangan subdistrict, North Jakarta, involving 205 subjects to analyze appropriate fixed-dose combination (FDC) anti-TB drug administration and an experimental study involving 23 control group TB patients and 23 intervention group TB patients to assess the benefit of supervision by each patient’s drug supervisor. Results: The association of FDC anti-TB drug side effects with the success of TB treatment was not statistically significant (p=0.173). There was an increase in drug supervisor knowledge of 8.6% in the intervention group and 13% in the control group. There was no statistically significant association between the knowledge of the drug supervisor and the 2nd month (p=0.575) and the 6th month of sputum treatment. Conclusion: Minor side effects of FDC anti-TB drug did not affect the success of TB treatment; therefore, treatment was continued if these adverse events occurred. There were no correlations between the drug supervisor knowledge level with medication compliance or with sputum conversion (months 2 and 6).

Original languageEnglish
Pages (from-to)272-276
Number of pages5
JournalInternational Journal of Applied Pharmaceutics
Volume11
DOIs
Publication statusPublished - 1 Apr 2019

Keywords

  • Drug supervisor
  • Fixed-dose combination
  • Tuberculosis

Fingerprint Dive into the research topics of 'Analysis of tuberculosis treatment suitability and the drug supervisor’s role in a community health center in pademangan subdistrict, north jakarta'. Together they form a unique fingerprint.

  • Cite this