Analysis of morphology and absorption of calcium and magnesium for calcium phosphate Ca3(PO4)2 in rat's spine

M. N. Ramahwati; A. L. Juwono; D. S. Soejoko; N. N. Mulyaningsih

doi:10.1088/1757-899X/496/1/012039

Analysis of morphology and absorption of calcium and magnesium for calcium phosphate Ca₃(PO₄)₂ in rat's spine

M. N. Ramahwati, A. L. Juwono, D. S. Soejoko, N. N. Mulyaningsih

Department of Physics

Research output: Contribution to journal › Conference article › peer-review

1 Citation (Scopus)

Abstract

The decline in bone mass is a sign of metabolic diseases called osteoporosis. Osteoporosis can be treated by adding the calcium level in the form of nano sized Ca₃(PO₄)₂. One type of calcium which can build and strengthen the bones is Ca₃(PO₄)₂. This study aimed to determine the effectively of nano sized Ca₃(PO₄)₂ addition which can be absorbed by rat bones and to identify the crystalline structure that was formed in rat bones with a specific purified diet. Nano sized Ca₃(PO₄)₂ was varied in a composition 0.5X, 1.0X and 1.5X compared to the normal needs in the purified diet. The rats were harvested in every two weeks, then their spines were taken to be investigated. The rat's spines were examined by using X-Ray Diffraction (XRD) and Atomic Absorption Spectroscopy (AAS). The effective amount of calcium for the rats was at the value of 0.5X. The amount of Ca as a bone mineral increased as the increasing amount of nano sized Ca₃(PO₄)₂, while the amount of Mg tended to fluctuate. The crystalline structure of hexagonal type was found in the rat bones with. Lattice parameters of a = 9.50 A and c = 6.83 A.

Original language	English
Article number	012039
Journal	IOP Conference Series: Materials Science and Engineering
Volume	496
Issue number	1
DOIs	https://doi.org/10.1088/1757-899X/496/1/012039
Publication status	Published - 22 Feb 2019
Event	2nd International Conference on Current Progress in Functional Materials 2017, ISCPFM 2017 - Bali, Indonesia Duration: 8 Nov 2017 → 9 Nov 2017

Keywords

atomic absorption spectroscopy
Ca(PO)
hydroxyapatite
purified diet
X-Ray Diffraction

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10.1088/1757-899X/496/1/012039

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title = "Analysis of morphology and absorption of calcium and magnesium for calcium phosphate Ca3(PO4)2 in rat's spine",

abstract = "The decline in bone mass is a sign of metabolic diseases called osteoporosis. Osteoporosis can be treated by adding the calcium level in the form of nano sized Ca3(PO4)2. One type of calcium which can build and strengthen the bones is Ca3(PO4)2. This study aimed to determine the effectively of nano sized Ca3(PO4)2 addition which can be absorbed by rat bones and to identify the crystalline structure that was formed in rat bones with a specific purified diet. Nano sized Ca3(PO4)2 was varied in a composition 0.5X, 1.0X and 1.5X compared to the normal needs in the purified diet. The rats were harvested in every two weeks, then their spines were taken to be investigated. The rat's spines were examined by using X-Ray Diffraction (XRD) and Atomic Absorption Spectroscopy (AAS). The effective amount of calcium for the rats was at the value of 0.5X. The amount of Ca as a bone mineral increased as the increasing amount of nano sized Ca3(PO4)2, while the amount of Mg tended to fluctuate. The crystalline structure of hexagonal type was found in the rat bones with. Lattice parameters of a = 9.50 A and c = 6.83 A.",

keywords = "atomic absorption spectroscopy, Ca(PO), hydroxyapatite, purified diet, X-Ray Diffraction",

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AU - Ramahwati, M. N.

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AU - Soejoko, D. S.

AU - Mulyaningsih, N. N.

N1 - Publisher Copyright: © Published under licence by IOP Publishing Ltd.

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N2 - The decline in bone mass is a sign of metabolic diseases called osteoporosis. Osteoporosis can be treated by adding the calcium level in the form of nano sized Ca3(PO4)2. One type of calcium which can build and strengthen the bones is Ca3(PO4)2. This study aimed to determine the effectively of nano sized Ca3(PO4)2 addition which can be absorbed by rat bones and to identify the crystalline structure that was formed in rat bones with a specific purified diet. Nano sized Ca3(PO4)2 was varied in a composition 0.5X, 1.0X and 1.5X compared to the normal needs in the purified diet. The rats were harvested in every two weeks, then their spines were taken to be investigated. The rat's spines were examined by using X-Ray Diffraction (XRD) and Atomic Absorption Spectroscopy (AAS). The effective amount of calcium for the rats was at the value of 0.5X. The amount of Ca as a bone mineral increased as the increasing amount of nano sized Ca3(PO4)2, while the amount of Mg tended to fluctuate. The crystalline structure of hexagonal type was found in the rat bones with. Lattice parameters of a = 9.50 A and c = 6.83 A.

AB - The decline in bone mass is a sign of metabolic diseases called osteoporosis. Osteoporosis can be treated by adding the calcium level in the form of nano sized Ca3(PO4)2. One type of calcium which can build and strengthen the bones is Ca3(PO4)2. This study aimed to determine the effectively of nano sized Ca3(PO4)2 addition which can be absorbed by rat bones and to identify the crystalline structure that was formed in rat bones with a specific purified diet. Nano sized Ca3(PO4)2 was varied in a composition 0.5X, 1.0X and 1.5X compared to the normal needs in the purified diet. The rats were harvested in every two weeks, then their spines were taken to be investigated. The rat's spines were examined by using X-Ray Diffraction (XRD) and Atomic Absorption Spectroscopy (AAS). The effective amount of calcium for the rats was at the value of 0.5X. The amount of Ca as a bone mineral increased as the increasing amount of nano sized Ca3(PO4)2, while the amount of Mg tended to fluctuate. The crystalline structure of hexagonal type was found in the rat bones with. Lattice parameters of a = 9.50 A and c = 6.83 A.

KW - atomic absorption spectroscopy

KW - Ca(PO)

KW - hydroxyapatite

KW - purified diet

KW - X-Ray Diffraction

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Y2 - 8 November 2017 through 9 November 2017

ER -

Analysis of morphology and absorption of calcium and magnesium for calcium phosphate Ca₃(PO₄)₂ in rat's spine

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Keywords

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