TY - JOUR
T1 - Analysis of body mass index, waist circumference, and body fat in predicting insulin resistance of polycystic ovary syndrome
AU - Harzif, Achmad Kemal
AU - Yusuf, Dwiyanarsi
AU - Silvia, Melisa
AU - Wiweko, Budi
AU - Hestiantoro, Andon
N1 - Publisher Copyright:
© 2017 American Scientific Publishers. All rights reserved.
PY - 2017/7
Y1 - 2017/7
N2 - Introduction: Polycystic Ovary Syndrome (PCOS) can be found in 5–10% women in reproductive age. Insulin resistance plays role in 50–80% PCOS patients. Many methods of measurement has been established to determine insulin resistance. However, all method of measurements are invasive, expensive, and inaccessible in remote area. Objectives: To assess whether Body Mass Index (BMI), waist circumference and body fat can be used as predicting variables of insulin resistance in PCOS patients and to assess variables’ cut off point. Method: This was a cross-sectional study of BMI, waist circumference, and body fat to assess insulin resistance in PCOS patients. A diagnostic study with observations that can be a predictor of insulin resistance in PCOS patients. Samples of this study were 61 women with PCOS. Results: There were 47 subjects (77%) with insulin resistance and 14 subjects (23%) who were not insulin resistance. All of three variables were statistically significant, there were BMI (p = 0.001, cut-off point value = 24.75 kg/m2, sensitivity = 72.3%, and specificity = 71.4%), waist circumference (p = 0.004, cut off point value = 86.5 cm, sensitivity = 68.1%, and specificity = 71.4%), and body fat (p =0.005, cut-off point value=36.15%, sensitivity =68.1%, and specificity =64.3%). Conclusion: BMI, waist circumference and body fat can be used as predictors of insulin resistance in PCOS women.
AB - Introduction: Polycystic Ovary Syndrome (PCOS) can be found in 5–10% women in reproductive age. Insulin resistance plays role in 50–80% PCOS patients. Many methods of measurement has been established to determine insulin resistance. However, all method of measurements are invasive, expensive, and inaccessible in remote area. Objectives: To assess whether Body Mass Index (BMI), waist circumference and body fat can be used as predicting variables of insulin resistance in PCOS patients and to assess variables’ cut off point. Method: This was a cross-sectional study of BMI, waist circumference, and body fat to assess insulin resistance in PCOS patients. A diagnostic study with observations that can be a predictor of insulin resistance in PCOS patients. Samples of this study were 61 women with PCOS. Results: There were 47 subjects (77%) with insulin resistance and 14 subjects (23%) who were not insulin resistance. All of three variables were statistically significant, there were BMI (p = 0.001, cut-off point value = 24.75 kg/m2, sensitivity = 72.3%, and specificity = 71.4%), waist circumference (p = 0.004, cut off point value = 86.5 cm, sensitivity = 68.1%, and specificity = 71.4%), and body fat (p =0.005, cut-off point value=36.15%, sensitivity =68.1%, and specificity =64.3%). Conclusion: BMI, waist circumference and body fat can be used as predictors of insulin resistance in PCOS women.
KW - Body fat
KW - Body mass index
KW - Insulin resistance
KW - PCOS
KW - Waist circumference
UR - http://www.scopus.com/inward/record.url?scp=85030214137&partnerID=8YFLogxK
U2 - 10.1166/asl.2017.9403
DO - 10.1166/asl.2017.9403
M3 - Article
AN - SCOPUS:85030214137
SN - 1936-6612
VL - 23
SP - 6807
EP - 6810
JO - Advanced Science Letters
JF - Advanced Science Letters
IS - 7
ER -