An atypical case: RT-PCR-negative, sero-positive covid-19 patient un caz atipic: Pacient COVID 19 seropozitiv, RT-PCR negativ

William Suriady, Andika chandra Putra, Wiwien heru Wiyono, Mohammad fahmi Alatas, Bettia Bermawi, Ratna Moniqa, Hendra Koncoro, Laurentius aswin Pramono, Fransiska, Maria edith Sulistio, Ramzi, Robert Sinto, Rachmat Hamonangan, Adi surya Komala, C. Krismini dwi irianti, J.b. Endrotomo sumargono

Research output: Contribution to journalArticlepeer-review

Abstract

The novel coronavirus disease-2019 (COVID-19), caused by the severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has become a public health emergency of international concern. The first confirmed COVID-19 case in Indonesia was announced on 2 March 2020, and later on, 11,192 confirmed cases were reported as of 3 May. The World Health Organization has stated that performing a real-time reverse transcription-polymerase chain reaction (RT-PCR) specific for SARS-CoV-2 on specimens from the upper and the lower respiratory tracts, especially nasopharyngeal and oropharyngeal swabs, is the standard diagnostic procedure for COVID-19. In Indonesia, we also use other diagnostic tests, such as rapid antibody tests specific for SARS-CoV-2. Herein, we report an atypical case of COVID-19 and describe the diagnostic process, the clinical course, with progression to severe pneumonia on Week 3 of illness and the case management. We also try to highlight the possibility of false-negative RT-PCR tests.

Original languageEnglish
Pages (from-to)107-114
Number of pages8
JournalPneumologia
Volume69
Issue number2
DOIs
Publication statusPublished - 1 Dec 2020

Keywords

  • atypical case
  • COVID-19
  • RT-PCR
  • SARS-CoV-2
  • sero-positive

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