The number of corruption can reduce by corruption prevention initiative. This research aims to improve the E-Tendering Electronic Procurement System (EPS) to be more transparent, accountable, and effective in preventing corruption and support the Corruption Eradication Commission (CEC). Management Information System and Business Process Reengineering methods are used in this study. The information system design proposed in this research made with a structured system development method consists of 4 stages; the creation of entity-relationship diagrams (ERD), relational database, use case diagram, and data flow diagram (DFD). This research provides three choices of scenarios that are modeled and simulated by iGrafx software. The most realistic scenario to be implemented right now is the first scenario with database integration for government agencies' administrative documents. The first scenario's benefit is reducing average cycle time by 34.20%, faster bid evaluation process, and eliminating face-to-face processes to prevent collusion. Scenario 3 is the ideal scenario to be implemented in a long-term project. The third scenario's benefit is reducing average cycle time by 18.34%, a faster bid evaluation process, eliminating face-to-face processes to prevent collusion, strengthening E-Tendering supervision with Self Monitoring, Analysis, Reporting Technology (SMART), and increase information transparency.